Sort   by:  
 Page size 
ProteomicsCharacterization of a nonhuman primate model for the study of testicular peritubular cells – comparison with human testicular cells
Smooth-muscle-like peritubular cells make up the wall of semniferous tubules of men. These human testicular peritubular cells (HTPC) have been shown to fulfill different roles. They transport sperm, secrete various factors like GDNF (glial cell line derived neurotrophic factor) and are immunological...
ORGANISM(S): Callithrix jacchus 
2018-06-06 | PXD009394 | Pride
Testis Mktpc Marmoset monkey Peritubular testicular cells Maxquant Htpc Dda Proteome 
TranscriptomicsMiRNA expression profiles of trophoblastic cells
To gain more insight in the expression and role of microRNAs in trophoblastic cells, we have assessed the miRNA expression pattern of four trophoblastic cell lines and have compared them with the miRNA signature of human isolated 3rd trimester cytotrophoblast cells. Total RNA was reverse-transcribed...
ORGANISM(S): Homo sapiens 
2011-09-22 | E-GEOD-32346 | biostudies-arrayexpress
TranscriptomicsGain of chromatin loops marks the exit from naïve pluripotency – in-situ Hi-C data
In-situ Hi-C data for mouse embryonic stem cells (ES cells, grown in the presence of FBS and LIF) and for NS cells.
ORGANISM(S): Mus musculus 
2018-11-08 | E-MTAB-6591 | biostudies-arrayexpress
ProteomicsEngineered Peptide Barcodes for Binding Protein Generation
Binding protein generation relies on laborious screening cascades that process candidate molecules individually. To break with this paradigm, we developed NestLink, a binder selection and identification technology able to biophysically characterize thousands of library members at once without handli...
ORGANISM(S): synthetic construct (code 12) 
2019-01-15 | PXD009301 | Pride
Peptide barcode 
ProteomicsAge-related alterations in the testicular proteome of a non-human primate
Aging of the human testis and associated cellular changes are difficult to assess, thus we used a translational non-human primate model to get insights into underlying biochemical processes. Using proteomics we analyzed testicular tissue of six young (age 2 to 3) and four old (age 10 to 12) C. jacch...
ORGANISM(S): Callithrix jacchus 
2021-06-21 | PXD024844 | Pride
Tpcs Testicular peritubular cells Aging Testicular aging Senescence Testis 
ProteomicsProteomic insights into senescence of testicular peritubular cells from a nonhuman primate model
Age-related changes of the human testis may include morphological alterations, disturbed steroidogenesis and impaired spermatogenesis. However, the specific impact of cell age remains poorly understood and difficult to assess. Testicular peritubular cells fulfill essential functions, including sperm...
ORGANISM(S): Callithrix jacchus 
2020-11-18 | PXD022165 | Pride
Testis Cellular model Marmoset monkey Ageing Proteome Senescence Secretome Non-human primate 
ProteomicsHuman Granulosa Cells Proteome
Human granulosa cells are follicular cells surrounding the oocyte. Human granulosa cells are retrieved during in vitro fertilization a process where patients undergo hormonal stimulation including FSH and LH/hCG stimulation. Under the influence of the luteinizing hormone (LH) a process called lutein...
ORGANISM(S): Homo sapiens (Human) 
2019-03-07 | PXD010658 | Pride
Human granulosa cells Bottom-up Corpus luteum Luteal cells Maxquant Shotgun proteomics Human reproduction Lc-ms/ms 
TranscriptomicsSurface Topography Enhances Differentiation of Mesenchymal Stem Cells Towards Osteogenic and Adipogenic Lineages
Surface topography impacts on cell growth and differentiation, but it is not trivial to generate homogeneous surface structures and to define the specific morphological parameters of relevance. In this study, we have compared gene expression profiles of mesenchymal stem cells (MSCs) on nanostructure...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-61113 | biostudies-arrayexpress
GenomicsGain of chromatin loops marks the exit from naive pluripotency - ChIP seq for CTCF and Rad21
ChIP-seq to map the binding sites for CTCF and cohesin subunit Rad21 in the naive mES cells (46C cell line grown in the 2i/LIF condition) and in the neural stem cells (derived from the 46C ES cells using the mono-layer differentiation protocol, grown in the N2B27 medium these cells are Nestin+)....
ORGANISM(S): Mus musculus 
2018-11-08 | E-MTAB-5732 | biostudies-arrayexpress
TranscriptomicsRNAi knock down of AURKA in human neuroblastoma IMR-32 cells
IMR-32 cells were infected either with control-shRNA or one of two different AURKA-shRNA vectors to identify genes regulated after AURKA knockdown.
ORGANISM(S): Homo sapiens 
2008-06-01 | E-MEXP-1496 | biostudies-arrayexpress
Sort   by:  
 Page size