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TranscriptomicsIdentification of quantitative trait loci controlling gene expression during the innate immunity response of soybean
Microbe associated molecular pattern (MAMP)-responsive genes were identified in leaves of four different genotypes. The genotypes used in this study were: LD0-2817P; LDX01-1-65; Ripley and EF59. Leaves from three-weeks old plants were used in this study We used microarray to identified the MAMP-resp...
ORGANISM(S): Glycine max 
2011-10-05 | E-GEOD-32642 | biostudies-arrayexpress
UnknownCharacterizing replicability in the clustering structure of brain morphology in autism, attention-deficit/hyperactivity disorder, and obsessive compulsive disorder
Not available
S-EPMC12398515 | biostudies-literature
TranscriptomicsTranscription profiling of rat aortic smooth muscle cells after PDGF-BB treatment
Unlike other terminally differentiated cell types, vascular SMCs display remarkable phenotypic plasticity. The adult, differentiated state is traditionally defined by expression of well-characterized SMC contractile genes. Extracellular cues, however, can induce contractile SMCs to remodel toward a ...
ORGANISM(S): Rattus norvegicus 
2009-12-02 | E-GEOD-19106 | biostudies-arrayexpress
TranscriptomicsDysregulation of Macrophage Activation Profiles by Engineered Nanoparticles
To investigate how the phenotype of macrophages that have engulfed engineered nanoparticles (ENPs) differs from normal macrophages, we conducted Affymetrix microarray studies to identify the gene regulatory pathways affected by the ENPs. To mimic potential occupational exposure scenarios, the exper...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-44294 | biostudies-arrayexpress
TranscriptomicsTransformation of the intestinal epithelium by the MSI2 RNA binding protein
The MSI2 RNA binding protein has recently emerged as a potent oncogene playing key roles in hematopoietic stem cell homeostasis and malignant hematopoiesis. Here we demonstrate that MSI2 is expressed in the intestinal stem cell compartment, that its expression is elevated in colorectal adenocarcinom...
ORGANISM(S): Mus musculus 
2014-12-20 | E-GEOD-64388 | biostudies-arrayexpress
TranscriptomicsRNase-mediated protein footprint sequencing reveals protein-binding sites throughout the human transcriptome
RNAs are continuously associated with RNA-binding proteins (RBPs), and these interactions are necessary for many key cellular processes ranging from splicing to chromatin regulation. Although numerous approaches have been developed to map RNA-binding sites of individual RBPs, few methods exist that ...
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-49309 | biostudies-arrayexpress
TranscriptomicsExpression data from asthamtic and healthy airway smooth muscle cells
Persistent severe asthma is associated with hyper-contractile airways and structural changes in the airway wall, including an increased airway smooth muscle (ASM) mass. This study used gene expression profiles from asthmatic and healthy airway smooth muscle cells grown in culture to identify novel r...
ORGANISM(S): Homo sapiens 
2015-01-31 | E-GEOD-63383 | biostudies-arrayexpress
TranscriptomicsExpression and ChIP-seq analyses of embryonic stem cells, extraembryonic endoderm stem cells, and trophoblast stem cells
Bivalent histone domains have been proposed to contribute to pluripotency in embryonic stem cells, suggesting an epigenetic mechanism may regulate stem cell behavior in general. Here we compare histone modifications in two other stem cells derived from the blastocyst. We show that extraembryonic ste...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-15519 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of normal and malignant human breast epithelial cells
Multiple genome-wide microarrays have been used to analyse the transcriptomes of immunomagnetically separated normal human luminal epithelial and myoepithelial cells, as well as primary malignant breast epithelial cells.
ORGANISM(S): Homo sapiens 
2006-09-29 | E-TABM-66 | biostudies-arrayexpress
TranscriptomicsSingle-Cell Transcriptomics of Acetaminophen-Induced Responses in Human 2D and 3D Liver Microtissues
This study aimed to investigate how liver cell culture architecture influences acetaminophen (APAP)-induced transcriptional responses at single-cell resolution. We used human liver microtissues composed of primary human hepatocytes (PHHs), Kupffer cells (KCs), and hepatic sinusoidal endothelial cell...
ORGANISM(S): Homo sapiens 
2025-09-01 | E-MTAB-15516 | biostudies-arrayexpress
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