Sort   by:  
 Page size 
TranscriptomicsOverexpression of NtmybA2 in tobacco BY-2 cells
Promoters of many G2/M phase-specific genes in plants contain mitosis-specific activator (MSA) elements, which act as G2/M phase-specific enhancers and bind with R1R2R3-Myb transcription factors. A least three R1R2R3-Myb proteins are expressed in tobacco (Nicotiana tabacum). To examine the genome-wi...
ORGANISM(S): Nicotiana tabacum 
2010-05-22 | E-GEOD-14251 | biostudies-arrayexpress
TranscriptomicsXenopus M-phase extract treated induced pluripotent stem cells
Transfer of somatic cell nuclei to enucleated eggs or ectopic expression of specific transcription factors are two different reprogramming strategies used to generate pluripotent cells from differentiated cells. However, they are poorly efficient and other unknown factors might be required to increa...
ORGANISM(S): Mus musculus 
2011-11-21 | E-GEOD-31691 | biostudies-arrayexpress
MetabolomicsDetermination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets
Spatial metabolomics using mass spectrometry imaging (MSI) is a powerful tool to map hundreds to thousands of metabolites in biological systems. One major challenge in MSI is the annotation of m/z values, which is substantially complicated by background ions introduced throughout the c...
2021-06-15 | MTBLS954 | MetaboLights
TranscriptomicsRedifferentiation of adult human M-NM-2 cells expanded in vitro by inhibition of the WNT pathway
In vitro expansion of adult human islet M-NM-2 cells is an attractive solution for the shortage of tissue for cell replacement therapy of type 1 diabetes. Using a lineage tracing approach, we have demonstrated that M-NM-2-cell-derived (BCD) cells rapidly dedifferentiate in culture and can proliferat...
ORGANISM(S): Homo sapiens 
2014-08-27 | E-GEOD-60803 | biostudies-arrayexpress
TranscriptomicsTranscriptome of Mycoplasma genitalium under osmotic stress
Mycoplasma genitalium is the causative agent of non-gonococcal, chlamydia-negative urethritis in men and has been linked to reproductive tract disease syndromes in women. As with other mycoplasmas, M. genitalium lacks many regulatory genes because of its streamlined genome and total dependence on a ...
ORGANISM(S): Mycoplasma genitalium 
2010-11-15 | E-GEOD-22661 | biostudies-arrayexpress
TranscriptomicsHomogeneous monocytes and macrophages from hES cells following coculture-free differentiation in M-CSF and IL-3.
In the present study we aimed at producing homogeneous populations of monocytes and macrophages from human embryonic stem (hES) cells. Human embryonic stem cell lines KCL001, KCL002, and HUES-2 were differentiated into monocytes by coculture-free differentiation with two growth factors using a three...
ORGANISM(S): Homo sapiens 
2010-05-08 | E-GEOD-15791 | biostudies-arrayexpress
TranscriptomicsQuantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution
Phenotypic differences between closely related species are thought to arise primarily from changes in gene expression due to mutations in cis-regulatory sequences (enhancers). However, it has remained unclear, how frequently mutations alter enhancer activity or create functional enhancers de novo. H...
ORGANISM(S): Drosophila willistoni 
2014-04-28 | E-GEOD-48251 | biostudies-arrayexpress
TranscriptomicsTranscriptome profile of human pancreatic beta cell line (EndoC-M-NM-2H2 ) following knockdown of RFX6.
RFX6 is a key transcription factor for the development of mouse pancreas, however the functional roles of RFX6 in human beta cells are poorly explored. Thus transcriptome analysis was perfomed to determine the functional targets of RFX6 in human beta cells using the recently developed human beta cel...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-GEOD-59049 | biostudies-arrayexpress
UnknownQuKAN: A Quantum Circuit Born Machine Approach to Quantum Kolmogorov Arnold Networks.
Not available
S-EPMC12511409 | biostudies-literature
TranscriptomicsSodium arsenite induced gene expression changes in A549 human epithelial lung carcinoma cells
Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns which could lead to altered gene expression Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 ...
ORGANISM(S): Homo sapiens 
2014-09-17 | E-GEOD-44169 | biostudies-arrayexpress
Sort   by:  
 Page size