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MetabolomicsDetoxification metabolic adaptation of Bombyx mori to artificial diet and functional study of key detoxification gene BmGSTd2

The exceptional adaptability of insects to diverse food sources is central to their survival and evolutionary success. However, the molecular mechanisms underlying this rapid adaptation remain largely uncharacterized. In this study, adaptive phenotypic, transcriptomic, and metabolomic differences...

2026-01-27 | MTBLS13782 | MetaboLights
TranscriptomicsmRNA time-course transcription profiling of bacteriocytes and gut tissue of pea aphids reared on standard artificial diet (AP3) and artificial diet depleted in Tyr and Phe (YFØ)
Tyrosine (Tyr, Y) and phenylalanine (Phe, F) synthesis is shared by the pea aphid and its symbiont Buchnera aphidicola.These aromatic amino acids are essential for the pea aphid growth and development. To characterize the molecular mechanisms, at gene transcriptional level, underlying this symbiotic...
ORGANISM(S): Acyrthosiphon pisum 
2017-07-18 | E-MTAB-4456 | biostudies-arrayexpress
TranscriptomicsMaternal Western-style high fat diet induces sex-specific physiological and molecular changes in two-week-old mouse offspring
Maternal diet is associated with the development of metabolism-related and other non-communicable diseases in offspring. Underlying mechanisms, functional profiles, and molecular markers are only starting to be revealed. Here, we explored the physiological and molecular impact of maternal Western-st...
ORGANISM(S): Mus musculus 
2013-11-27 | E-GEOD-46359 | biostudies-arrayexpress
ProteomicsInvestigation of the protein profile of silkworm (Bombyx mori) pupae reared on a well-calibrated artificial diet compared to mulberry leaf diet
Background. Silkworm pupae (SWP) is the main by-product of the sericulture industry with an interesting nutritional profile, especially in terms of proteins. In consideration of its possible use as a food or food ingredient in Western countries, a comparative proteomic experiment has been performed ...
ORGANISM(S): Bombyx mori (Silk moth) 
2019-06-03 | PXD012869 | Pride
Proteomics Bombyx mori Lc-ms/ms 
TranscriptomicsA weekly alternating diet between caloric restriction and medium fat protects the liver from NAFLD in middle aged C57BL/6J mice
SCOPE: We investigated whether a novel dietary intervention consisting of an every-other-week calorie-restricted diet could prevent nonalcoholic fatty liver disease (NAFLD) development induced by a medium-fat (MF) diet. METHODS AND RESULTS: Nine-week-old male C57BL/6J mice received either a (i) cont...
ORGANISM(S): Mus musculus 
2015-10-26 | E-GEOD-61233 | biostudies-arrayexpress
TranscriptomicsEffects of diet and age on canine liver gene expression
The liver is the central organ in the regulation of nutrient metabolism, xenobiotic metabolism, and detoxification. Aging leads to a marked change in liver structure and function, characterized by a decline in weight, blood flow, regeneration rate, and detoxification. However, the mechanisms that ...
ORGANISM(S): Canis lupus familiaris 
2011-01-01 | E-GEOD-22945 | biostudies-arrayexpress
ProteomicsProteomics analysis of Bemisia tabaci (MED) saliva
The saliva from Bemisia tabaci (MED biotype) adults was collected using an artificial feeding system and analyzed using an LC-MS/MS proteomics analysis.
ORGANISM(S): Bemisia tabaci 
2024-01-26 | PXD033180 | Pride
Artificial diet Bemisia Whitefly Saliva 
TranscriptomicsSRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass
Increased expression of SIRT1 extends the lifespan of lower organisms and delays the onset of age-related diseases in mammals. Here, we show that SRT2104, a synthetic small molecule activator of SIRT1, extends both mean and maximal lifespan of mice fed a standard diet. This is accompanied by improve...
ORGANISM(S): Mus musculus 
2014-09-22 | E-GEOD-49000 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of physiological pathways in a generalist herbivore: responses to different host plants and plant structures by the cotton bollworm (CBW) Helicoverpa armigera [DifferentHost]
Transcriptional profiling comparing gut tissue from fifth instar larvae exposed to six different diets, namely cotton fruit or boll (B), tobacco flower bud (TFB), bean pod (BP), chick pea fruit (CKPF), pinto bean-based artificial diet (PB) and wheat-based artificial Lepidoptera diet (BIO). The gener...
ORGANISM(S): Helicoverpa armigera 
2011-12-12 | E-GEOD-34346 | biostudies-arrayexpress
TranscriptomicsHigh dietary protein decreases fat deposition induced by high-fat and high-sucrose diet in rats
High-protein diets are known to reduce adiposity in the context of high carbohydrate and Western diets. However, few studies have investigated the specific high-protein effect on lipogenesis induced by a high-sucrose (HS) diet or fat deposition induced by high-fat feeding. We aimed to determine the ...
ORGANISM(S): Rattus norvegicus 
2015-09-01 | E-GEOD-47570 | biostudies-arrayexpress
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