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TranscriptomicsMixed-polarization phenotype of ascites-associated macrophagesin human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse
Ascites-associated macrophages were collected from human ovarian carcinoma patients and their expression profiles determined via Agilent microarrays. In addition, monocyte derived macrophages from healthy donors were differentiated ex-vivo with MCSF and GMCSF and their expression profiles determined...
ORGANISM(S): Homo sapiens 
2014-03-07 | E-MTAB-1661 | biostudies-arrayexpress
ProteomicsProteome profiling of ovarian cancer and cirrhosis ascites
Proteome-metabolome profiling of ovarian cancer ascites reveals novel components involved in intercellular communication http://www.mcponline.org/content/early/2014/09/30/mcp.M114.041194.full.pdf+html?sid=78e7a955-fa54-4ded-b296-89f1fb6adbec
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079934 | MassIVE
TranscriptomicsAscites enriches for ovarian cancer stem-like cells that express membrane GRP78
Ovarian cancer patients are generally diagnosed at stage III/IV, when ascites is common. The volume of ascites positively correlates with the extent of metastasis and negatively with prognosis. Membrane GRP78, a stress-inducible endoplasmic reticulum chaperone which also appears on the plasma membra...
ORGANISM(S): Mus musculus 
2015-03-09 | E-GEOD-61285 | biostudies-arrayexpress
ProteomicsGlycomic and proteomic analyses of malignant ascites fluid were used to identify potential metastatic biomarkers of epithelial ovarian cancer : Partial
Ovarian cancer is a major cause of cancer mortality among women largely due to late diagnosis of advanced stage metastatic disease. More extensive molecular analysis of metastatic ovarian cancer is needed to identify post-translational modifications of proteins particularly associated with metastati...
ORGANISM(S): Homo sapiens (Human) 
2016-08-15 | PXD003794 | Pride
Ascites Concanavalin a Epithelial ovarian cancer 
ProteomicsGastric cancer ascites proteome
Gastric cancer is one of the most lethal malignancies with high mortality and gastric cancer-specific biomarker is need due to the lack of specific method for early screening, diagnosis, and prognosis of the patients with gastric cancer. Ascites is known for an important source for conducing biomark...
ORGANISM(S): Homo sapiens (Human) 
2018-04-16 | PXD002213 | Pride
Proteome profiling Proteomics Ascites Gastric cancer Biomarker 
ProteomicsIsolation of EVs from Minimal Ascites Fluid Volume
Using Mag-Net beads to capture EVs from murine and human ascites fluid. Determine minimal volume of starting material needed for parallel proteomics and SERS analysis.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-09-07 | PXD068766 | Pride
Ovarian cancer Dia Extracellular vesicles Ascites Mag-net 
GenomicsChIP-seq of tumour associated macrophages derived from high grade ovarian serous carcinoma patient ascites
Tumor associated macrophages of one patient were assayed for histone modifications, methylation (MIRA) and CEBP.
ORGANISM(S): Homo sapiens 
2018-08-13 | E-MTAB-6297 | biostudies-arrayexpress
ProteomicsProtein enrichment of human ascites fluid using Nanotrap hydrogel particle technology DIA
Compare protein and peptide identification, technical reproducibility, proteome depth, dynamic range, and gene ontology enrichment of ascites fluid. Enrichment will selectively isolate low abundance proteins and exclude high abundance proteins, enhancing depth of proteomic coverage.
ORGANISM(S): Homo sapiens (Human) 
2026-09-08 | PXD076432 | Pride
ProteomicsProtein enrichment of human ascites fluid using Nanotrap hydrogel particle technology DDA
Compare protein and peptide identification, technical reproducibility, proteome depth, dynamic range, and gene ontology enrichment of ascites fluid. Enrichment will selectively isolate low abundance proteins and exclude high abundance proteins, enhancing depth of proteomic coverage.
ORGANISM(S): Homo sapiens (Human) 
2026-09-08 | PXD068693 | Pride
TranscriptomicsRole of malignant ascites on human mesothelial cells and their gene expression profiles
Background: Malignant ascites is often present at diagnostic in women with advanced ovarian cancer (OC) and its presence is associated with a worse outcome. Human peritoneal mesothelial cells (HPMCs) are key components of malignant ascites. Although the interplay between HPMCs and OC cells is believ...
ORGANISM(S): Homo sapiens 
2014-04-14 | E-GEOD-55065 | biostudies-arrayexpress
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