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MetabolomicsTraditional Chinese medicine Dachaihu decoction alleviates abnormal behavior through regulating gut microbiota and metabolites in children with ASD

Traditional Chinese Medicine Dachaihu decoction (DCHD) has been reported to hold great promise to alleviate autism spectrum disorders (ASD), a generalized neurodevelopmental disease associated with gut microbiome dysbiosis. Health-promoting effects of DCHD on ASD children could be attributed to g...

2025-12-12 | MTBLS13501 | MetaboLights
MetabolomicsMetabolomic Profiling of the Striatum in Shank3 Knockout ASD Rats: Effects of Early Swimming Regulation

OBJECTIVE: This study aimed to investigate the regulatory impact of early swimming intervention on striatal metabolism in Shank3 gene knockout ASD model rats.

METHODS: Shank3 gene knockout exon 11-21 male 8-day-old SD rats were used as experimental subject...

2024-09-27 | MTBLS8577 | MetaboLights
GenomicsASD Colorado Longitudinal
ASD Colorado Longitudinal
PRJEB42687 | ENA
GenomicsASD gut mycobiota
ASD gut mycobiota
PRJEB15420 | ENA
GenomicsASD+/+ and ASD+/- tumor stroma gene expression microarray comparison [microarray]
ASD+/+ and ASD+/- tumor stroma gene expression microarray comparison [microarray]
PRJNA1103164 | ENA
GenomicsASD rat feces
ASD rat feces Raw sequence reads
PRJNA606860 | ENA
ProteomicsA Pilot Proteomic Study of Protein Markers in Autism Spectrum Disorder
Autism spectrum disorder (ASD) diagnosis is increasing, with 1/88 children believed to be affected by the disorder, with a most recent survey suggesting numbers as high as 1/50. Treatment and understanding of ASD causes is a pressing health concern. ASD protein biomarkers may provide clues about ASD...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD000679 | Pride
Autism Cholesterol Apolipoprotein Oxidative stress Biomarkers Asd 
TranscriptomicsTranscriptome profiling in Engrailed2 knockout mice reveals common molecular pathways associated with ASD.
Background: Transcriptome analysis has been used in autism spectrum disorder (ASD) to unravel common pathogenic pathways based on the assumption that distinct rare genetic variants or epigenetic modifications affect common biological pathways dysregulated in ASD. To unravel recurrent ASD-related neu...
ORGANISM(S): Mus musculus 
2013-12-23 | E-GEOD-51612 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of autistic brain reveals convergent molecular pathology [high-throughput sequence data]
Autism spectrum disorder (ASD) is a common, highly heritable neurodevelopmental condition characterized by marked genetic heterogeneity. Thus, a fundamental question is whether autism represents an aetiologically heterogeneous disorder in which the myriad genetic or environmental risk factors pertur...
ORGANISM(S): Homo sapiens 
2011-07-12 | E-GEOD-30573 | biostudies-arrayexpress
TranscriptomicsInvestigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders (ASD) by microRNA expression profiling of lymphoblastoid cell lines
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by abnormalities in reciprocal social interactions and language development and/or usage, and by restricted interests and repetitive behaviors. Differential gene expression of neurologically relevant genes in lymphoblasto...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-21086 | biostudies-arrayexpress
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