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ProteomicsUlcerative Colitis-Derived Colonoid Culture: 2 A multi-mineral-approach to improve barrier protein expression
Background. Recent studies demonstrated that Aquamin®, a calcium-, magnesium-, and multiple trace element-rich natural product, improves barrier structure and function in colonoids obtained from the tissue of healthy subjects. The goal of the present study was to determine if the colonic barrier co...
ORGANISM(S): Homo sapiens (Human) 
2020-12-17 | PXD020244 | Pride
Basement membrane Desmosome Calcium Colonoid Cell barrier 29 proteomics Ulcerative colitis 
ProteomicsProteomic Profile of Human Colon Organoids: Effects of a multi-mineral intervention alone and in the presence of pro-Inflammatory and anti-inflammatory treatments
Introduction: Aquamin, a multi-mineral product derived from fossilized red marine algae, has been shown to improve colon barrier structure and function. Mesalamine is commonly used as maintenance therapy for patients with mild-to-moderate ulcerative colitis (UC) or those in remission. Our long-term ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD062086 | Pride
Ulcerative colitis Gut barrier Mesalamine Inflammation Aquamin Colon organoids 
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