Sort   by:  
 Page size 
GenomicsRole of Atg16L1 in skin biology
Role of Atg16L1 in skin biology
PRJNA906019 | ENA
TranscriptomicsRole of Atg16L1 in skin biology
In order to unravel the functional role of autophagy in skin homeostasis, we performed single-cell RNA-sequencing on total skin of 10-weeks-old male mice lacking ATG16L1 selectively in keratinocytes. Keratinocyte-specific ATG16L1 knock-out (KO) mice do not show an overt skin phenotype. By performing...
ORGANISM(S): Mus musculus 
2023-07-13 | GSE218854 | GEO
UnknownMacrophage ATG16L1 promotes liver regeneration after partial hepatectomy.
Not available
S-EPMC12023798 | biostudies-literature
ProteomicsInteractome of CD63 in WT and ATG16L1-KO cells
We use an MS-based proteomic approach to demonstrate the physical interaction between the exosomal marker CD63 and mutant huntingtin, likely occurring upon transfer of the latter within the MVBs compartment, confirming how such pathway diversion can indeed regard autophagy substrate proteins (and ot...
ORGANISM(S): Homo sapiens (Human) 
2026-05-13 | PXD076375 | Pride
GenomicsTumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer (bulk RNA-seq)
Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer (bulk RNA-seq)
PRJNA791686 | ENA
UnknownDeficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation.
Not available
S-EPMC6827317 | biostudies-literature
GenomicsTumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer (single cell RNA-seq)
Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer (single cell RNA-seq)
PRJNA791690 | ENA
TranscriptomicsTumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer (single cell RNA-seq)
We utilized 10X single cell RNA sequencing to investigate in murine liver how Atg16l1 deletion in AKPS colorectal cancer organoids impacted phenotypic programming of organoid cells and myeloid cells in the tumor microenvironment. Atg16l1 KO and Wt cells were inoculated into the liver of NSG mice via...
ORGANISM(S): Mus musculus 
2023-08-28 | GSE192514 | GEO
ProteomicsGlobal proteome of Atg16L1flox:CAG-CreTmx WT and KO neurons
The experiment was performed to identify autophagy targets in wildtype and autophagy-deficient primary neurons. Therefore, cortico-hippocampal neurons were isolated from Atg16L1flox:CAG-CreTmx mice and treated with Tamoxifen (Tmx) to induce the knockout (KO) or EtOH for wildtype (WT) in-vitro. WT an...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-15 | PXD031555 | Pride
Atg16l1 ko Neurons Autophagy 
UnknownZDHHC7-mediated <i>S</i>-palmitoylation of ATG16L1 facilitates LC3 lipidation and autophagosome formation.
Not available
S-EPMC11587844 | biostudies-literature
Sort   by:  
 Page size