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ProteomicsLoss of Atoh8 impairs macroautophagy
The basic helix-loop-helix (bHLH) transcription factor ‘Atoh8’ is involved in the regulaton of several developmental processes and pathologies. It regulates organogenesis, reprogramming, stem cell fate determination, and cancer development. However, the mech anisms underlying these observations rema...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-05 | PXD070896 | Pride
Metabolism Tfeb Atoh8 Ros Macroautophagy P62 Autophagy 
TranscriptomicsKnockdown of Atoh8 in Neurog3-expressing mouse ductal cells mPAC results in altered expression of multiple cell cycle related genes
Atoh8 is a transcription factor of the basic-helix-loop-helix (bHLH) family that is expressed in multiple tissues during embryonic development but whose specific functions remain unknown. The gene encoding Atoh8 is induced by various lineage- determining bHLH transcription factors in cell culture, ...
ORGANISM(S): Mus musculus 
2014-10-10 | E-GEOD-43536 | biostudies-arrayexpress
GenomicsUnraveling the role of ATOH8 in trophoblast lineage differentiation
Unraveling the role of ATOH8 in trophoblast lineage differentiation
PRJNA1244817 | ENA
UnknownLoss of Atoh8 Impairs Macroautophagy.
Not available
S-EPMC12731601 | biostudies-literature
GenomicsBcl11b and Atoh8 binding on chromatin in MEFs
Bcl11b and Atoh8 binding on chromatin in MEFs
PRJNA751042 | ENA
GenomicsbHLH transcription factor ATOH8 overexpression effect on endothelial cells: gain-of-function model [GOF]
bHLH transcription factor ATOH8 overexpression effect on endothelial cells: gain-of-function model [GOF]
PRJNA413501 | ENA
GenomicsbHLH transcription factor ATOH8 depletion effect on endothelial cells: loss-of-function model [LOF]
bHLH transcription factor ATOH8 depletion effect on endothelial cells: loss-of-function model [LOF]
PRJNA413502 | ENA
UnknownGeneration of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8).
Not available
S-EPMC4708992 | biostudies-literature
GenomicsATOH8 inhibits cell proliferation through transcriptional regulating cell cycle related genes [RNA-seq]
ATOH8 inhibits cell proliferation through transcriptional regulating cell cycle related genes [RNA-seq]
PRJNA785650 | ENA
GenomicsIdentification of genes upregulated and downregulated in mouse embryonic fibroblasts (MEFs) upon Atoh8 depletion
Identification of genes upregulated and downregulated in mouse embryonic fibroblasts (MEFs) upon Atoh8 depletion
PRJNA600996 | ENA
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