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Tumor cells with diverse phenotype and biological behaviors are influenced by stromal cells through secretory factors or direct cell-cell contact. Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive desmoplasia with fibroblasts as the major cell type. Here, we observed enrichment o...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD029467 | Pride
Analysis of aldosterone-producing adenoma (APA) samples from patients with primary hyperaldosteronism. These APAs have a somatic mutation in either KCNJ5, CACNA1D, or ATP1A1. Results provide insight into the different mechanisms each mutation may cause leading to elevated aldosterone production in A...
ORGANISM(S): Homo sapiens 
Analysis of aldosterone-producing adenoma (APA) samples from patients with primary hyperaldosteronism. These APAs have a somatic mutation in either KCNJ5, CACNA1D, or ATP1A1. Results provide insight into the different mechanisms each mutation may cause leading to elevated aldosterone production in A...
ORGANISM(S): Homo sapiens 
2013-07-14 | GSE48303 | GEO
Base editor induced mutation spectrum in GFP, human ATP1a1, human TP53BP1 and murine MyoD
Analysis of targeted genomic and epigenomic mutations within GFP, human ATP1a1, human TP53BP1 and murine MyoD induced through state-of the art base editors
ORGANISM(S): Homo sapiens Mus musculus 
2023-10-30 | GSE206445 | GEO
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