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GenomicsTranscriptomic analysis of ATP6V1A knock-down and amyloid beta-treated neurons
Transcriptomic analysis of ATP6V1A knock-down and amyloid beta-treated neurons
PRJNA527281 | ENA
ProteomicsRNA-binding proteins associating with the 3’UTR of the ATP6V1A transcript in SIRT1 knock-down cells
Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) binds various RNA transcripts and functions as a tumor promoter, although little is known regarding the mechanisms that regulate its roles in RNA metabolism (1-3). Here we find that IGF2BP2 binds to the 3’ untranslated region of the tran...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD028114 | Pride
Breast cancer Sirt1 Rna-binding proteins Human Atp6v1a 
TranscriptomicsTranscriptomic analysis of ATP6V1A knock-down and amyloid beta-treated neurons
ATP6V1A plays a unique role in synapse function in neurons and we found decreased neuronal activity in ATP6V1A-deficient neurons. To characterize the molecular pathways regulated by ATP6V1A under both normal and stressed conditions, we generated hiPSC-derived NGN2-neurons with reduced ATP6V1A expres...
ORGANISM(S): Homo sapiens 
2020-10-30 | GSE128367 | GEO
ProteomicsEndogenous pull-downs of human proteins ATP6V1A and AHNAK to validate interactions with influenza A virus proteins M2 and NEP by targeted mass spectrometry in virus-infected cells
Influenza A Virus (IAV) is a recurring respiratory virus with antiviral therapies of limited use. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry (AP-MS) and global phosphoprote...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD041663 | Pride
Virus-host Protein-protein interaction H5n1 Prm Human A549 Nhbe Influenza a virus 
UnknownPhenotypic and genetic spectrum of ATP6V1A encephalopathy: a disorder of lysosomal homeostasis.
Not available
S-EPMC10893886 | biostudies-literature
UnknownDownregulation of ATP6V1A Involved in Alzheimer's Disease via Synaptic Vesicle Cycle, Phagosome, and Oxidative Phosphorylation.
Not available
S-EPMC8087993 | biostudies-literature
UnknownThe ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein.
Not available
S-EPMC7949080 | biostudies-literature
UnknownExpanding the clinical and molecular spectrum of ATP6V1A related metabolic cutis laxa.
Not available
S-EPMC8638669 | biostudies-literature
UnknownDe novo mutations of the ATP6V1A gene cause developmental encephalopathy with epilepsy.
Not available
S-EPMC5972584 | biostudies-literature
UnknownMechanistic Study of Hypoxia-Mediated Regulation of Osteoblast Senescence via ATP6V1A-Dependent Modulation of Metabolic Remodeling.
Not available
S-EPMC12731071 | biostudies-literature
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