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TranscriptomicsAge-dependent gene expression profiles after hepatic ischemia/reperfusion in mice
Experimental Design: 1. The goal of the experiment: Age-Dependent Gene Expression Profiles After Hepatic Ischemia/Reperfusion: Implications for the AP-1 and Ubiquitin-Proteosome Pathways 2. Brief description of the experiment: Hepatic ischemia/reperfusion (I/R) injury is a complication of liver surg...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10654 | biostudies-arrayexpress
TranscriptomicsDivergent genome expression profiles during hepatic ischemia in young and adult mice
Experimental Design: 1. The goal of the experiment: Age-Related Genome Expression Profiles During Hepatic Ischemia 2. Brief description of the experiment: Hepatic ischemia/reperfusion (I/R) injury is a complication of liver surgery, transplantation and shock and differs with age. In the present stu...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10652 | biostudies-arrayexpress
TranscriptomicsHypertensive Study
Animals. Male Sprague–Dawley rats (Charles River Laboratories, Wilmington, MA) weighing about 250g were used. The study was approved by the Thomas Jefferson University Institutional Animal Care and Use Committee and was conducted in accordance with the National Institutes of Health Guide for the Car...
ORGANISM(S): unidentified 
2007-12-01 | E-GEOD-8585 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of male breast cancer
To test the hypothesis that there is a specific miRNA expression signature which characterizes male breast cancers, we performed miRNA microarray analysis in a series of male breast cancers and compared them to cases of male gynecomastia and female breast cancers miRNA microarray analysis was perfor...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-17155 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hepatic response to anti-diabetic drug and dietary lifestyle interventions in LDLR-/- mice
Lean male mice were fed a high fat diet (HFD, lard 24% w/w) for 16 weeks. At 9 weeks, when all hallmarks of prediabetes were established, groups of mice were treated with drug (metformin, glibenclamide, sitagliptin, rosiglitazone, pioglitazone, fenofibrate, T0901317, atorvastatin, salicylate or rofe...
ORGANISM(S): Mus musculus 
2013-04-18 | E-MTAB-1063 | biostudies-arrayexpress
GenomicsAuthentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1
Whole genome sequencing (WGS) from snap-frozen oesophageal tumour tissue and germline nucleic acids isolated from peripheral blood mononuclear cells (PBMC) was performed as part of the International Cancer Genome Consortium project and OCCAMS consortium (1,2). Filtered read sequences were mapped to ...
ORGANISM(S): Homo sapiens 
2016-09-09 | E-MTAB-4600 | biostudies-arrayexpress
TranscriptomicsGenomic profile of foamy and non-foamy granuloma macrophages from fat-fed ApoE null mice or control mice fed a normal diet
Formation of foam cell macrophages (FCMs), which sequester extracellular modified lipids, is a key event in atherosclerosis. How lipid loading affects macrophage phenotype is controversial, with evidence suggesting either pro- or anti-inflammatory consequences. To investigate this further, we compar...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-70126 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Drosophila cell line Dmel2
Deep Sequencing of mRNA from the Drosophila melanogaster cell line D.Mel-2 Analysis of poly(A)+ RNA of D.Mel-2 cell line
ORGANISM(S): Drosophila melanogaster 
2010-04-09 | E-GEOD-21283 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially expressed genes between clinical and bovine-biased Escherichia coli O157:H7 genotypes
Escherichia coli O157:H7 strains have been classified into different genotypes based on the presence of specific shiga toxin-encoding bacteriophage insertion sites. Genotypes that are predominant in clinical isolates are named clinical genotypes and those that are isolated mostly from bovine source...
ORGANISM(S): Escherichia coli 
2010-06-19 | E-GEOD-15783 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of adipose samples from LDLR-/- mice to study response to anti-diabetic drug and dietary lifestyle interventions
Lean male mice were fed a high fat diet (HFD, lard 24% w/w) for 16 weeks. At 9 weeks, when all hallmarks of prediabetes were established, groups of mice were treated with drug (rosiglitazone, pioglitazone, T0901317, or salicylate) for another 7 weeks together with the high fat diet. An additional gr...
ORGANISM(S): Mus musculus 
2014-05-14 | E-GEOD-57659 | biostudies-arrayexpress
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