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ProteomicsTranscriptomic profiling of epigenetic regulators and metabolic reprogramming in human cholangiocarcinoma
Background: Epigenetic alterations play an increasingly recognized role in carcinogenesis and in the development of resistance to anticancer therapies. Epigenetic enzymes (writers and erasers) and effectors (readers) are largely influenced by the availability of metabolites grenerated through one-ca...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD072211 | Pride
Metabolism Mouse models Epigenetics Drug targets Cholangiocarcinoma 
TranscriptomicsSlu7 is essential for liver differentiation, metabolism and quiescence
The equilibrium between cellular differentiation and proliferation is fundamental for tissue homeostasis. This is particularly important for the liver, a highly differentiated organ with systemic metabolic functions still endowed with unparalleled regenerative potential. Hepatocellular de-differenti...
ORGANISM(S): Homo sapiens 
2014-05-29 | E-GEOD-54090 | biostudies-arrayexpress
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S-EPMC7787219 | biostudies-literature
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