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TranscriptomicsTranscription profiling by microarray of lncRNA affected by EGF stimulation of MCF10A cells
Using basal‐like untransformed cells, MCF10A, as a model system, data from our laboratory showed that both mRNAs and microRNAs exhibit dynamic changes in expression following EGF stimulation (Amit et al, 2007; Avraham et al, 2010; Kostler et al, 2013). We further demonstrated that the inducible mRNA...
ORGANISM(S): Homo sapiens 
2017-07-27 | E-MTAB-4822 | biostudies-arrayexpress
UnknownStriatin is a novel modulator of cell adhesion.
Not available
S-EPMC6988865 | biostudies-literature
TranscriptomicsIdentification of microRNA targets in the mammalian inner ear using a comprehensive transcriptome and proteome integrated approach
We have employed a novel approach for the identification of functionally important microRNA (miRNA)-target interactions using integrated miRNA, transcriptome and proteome profiles with advanced in silico analysis. By looking at both the transcript and protein levels of expression, a thorough coverag...
ORGANISM(S): Mus musculus 
2011-04-20 | E-GEOD-23081 | biostudies-arrayexpress
UnknownPerforated Concave Earplug (pCEP): A Proof-of-Concept Earplug to Improve Sound Localization without Compromising Noise Attenuation.
Not available
S-EPMC10490414 | biostudies-literature
TranscriptomicsEGF decreases the abundance of microRNAs that restrain oncogenic transription factors
Epidermal growth factor (EGF) stimulates cells by launching gene expression programs that are frequently deregulated in cancer. MicroRNAs, which attenuate gene expression by binding complementary regions in messenger RNAs, are broadly implicated in cancer. Using genome-wide approaches, we showed tha...
ORGANISM(S): Homo sapiens 
2012-09-06 | E-GEOD-40626 | biostudies-arrayexpress
TranscriptomicsAnalysis of bacterial and macrophage transcripts in ISRE-positive and negative infected macrophages
To identify bacterial transcripts that may be associated with type I IFN production in Salmonella enterica subsp typhimurium (SL1344) infected macrophages we transformed macrophages with an ISRE-GFP reporter construct and sorted separate populations of GFP positive and GFP negative infected macropha...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65531 | biostudies-arrayexpress
TranscriptomicsSingle cell analysis of macrophages exposed to beads coated with LPS from Salmonella enterica subsp. typhimurium
We present a detailed single cell analysis of the macrophage response to LPS from Salmonella enterica. By combining single cell transcriptional analysis, fluorescently labeled, LPS-coated beads, and cytometry we are able to distinguish the responses of macrophages that have internalized LPS-coated ...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65529 | biostudies-arrayexpress
TranscriptomicsSingle cell time course of macrophages exposed to Salmonella enterica subsp. typhimurium
We present a detailed single cell time course of the macrophage response to Salmonella infection. By combining phenotypic fluorescent labels with single cell expression analysis we are able to identify gene modules associated with bacterial exposure and bacterial infection. We also identify other ...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65528 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq analysis of the macrophage response to Salmonella enterica subsp. Typhimurium (SL1344) exposure
A time course of the macrophage response to Salmonella exposure analyzing the effects of input cell number as a control for single cell studies Mouse macrophages were exposed to Salmonella enterica for different lengths of time. Libraries were constructed using either approximately 500,00 macrophag...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65530 | biostudies-arrayexpress
UnknownThe Loss of Myocardial Benefit following Ischemic Preconditioning Is Associated with Dysregulation of Iron Homeostasis in Diet-Induced Diabetes.
Not available
S-EPMC4961428 | biostudies-literature
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