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ProteomicsIn Silico Analysis Validates Proteomic Findings of Formalin-fixed Paraffin Embedded Cutaneous Squamous Cell Carcinoma Tissue
Background: Cutaneous squamous cell carcinoma (cSCC) is a common type of skin cancer but there are no comprehensive proteomic studies on this entity. Materials and Methods: We employed liquid chromatography coupled with tandem mass spectrometry (MS/MS) using formalin-fixed paraffin-embedded (FFPE) c...
ORGANISM(S): Homo sapiens (Human) 
2018-11-07 | PXD011492 | Pride
Cutaneous squamous cell carcinoma  formalin-fixed paraffin embedded  label-free mass spectrometry  laser capture microdissection  proteomics 
ProteomicsProteomic analysis of tape-stripped actininc keratosis
This project aims to evaluates Tape Stripping (TS) of stratum corneum (SC) for non-invasive proteomic analysis of AK using mass spectrometry approach.
ORGANISM(S): Homo sapiens (Human) 
2018-10-01 | PXD011000 | Pride
Tape-stripping Proteomics Actininc keratosis Lc-ms/ms 
ProteomicsDifferential proteomic analysis of actinic keratosis, Bowen's disease and cutaneous squamous cell carcinoma by label-free LC-MS/MS
BACKGROUND: The boundaries between actinic keratosis (AK), Bowen's disease (BD), and cutaneous squamous cell carcinoma (cSCC) are sometimes not clear. Large-scale proteomic profiling studies of these lesions are also non-existent. OBJECTIVE: To evaluate proteomic changes between normal epidermis, A...
ORGANISM(S): Homo sapiens (Human) 
2018-11-21 | PXD011609 | Pride
Actinic keratosis  bowen’s disease  cutaneous squamous cell carcinoma  mass spectrometry-based proteomics 
ProteomicsSpecialised skin cancer library spectral library for use in data independent mass spectrometry
A specialised spectral ion reference library for use in data independent acquisition mass spectrometry applications for the purposes of skin specific research with a particular focus on melanoma and keratinocytic carcinoma
ORGANISM(S): Homo sapiens (Human) 
2021-08-23 | PXD025791 | Pride
Proteomics Skin Keratinocytic Carcinoma Melanoma Human 
UnknownNovel coumarin-based acetohydrazide-1,2,3-triazole derivatives as urease enzyme inhibitors: Synthesis, in vitro evaluation, and molecular dynamics simulation studies.
Not available
S-EPMC11825259 | biostudies-literature
ProteomicsTape-Stripped Proteomics: A Comparative Analysis of Different Sample Collection Approaches
The study explores the impact of sampling surrounding normal-looking skin and the amount of pressure applied during the collection of stratum corneum samples using adhesive discs, aiming to improve the reproducibility of proteomic data in skin research. Researchers collected samples from six partici...
ORGANISM(S): Homo Sapiens (human) 
2025-11-05 | PXD057504 | JPOST Repository
ProteomicsNon-invasive proteomic signatures for the diagnosis and classification of keratinocytic skin lesions
This study used non-invasive sampling by tape-stripping coupled with data-independent acquisition mass spectrometry (DIA-MS) proteomics to profile the proteome of 61 histopathologically diagnosed Keratinocytic skin lesions (KSLs), including pre-malignant actinic keratosis (AK) and Bowen's disease (B...
ORGANISM(S): Homo Sapiens (human) 
2024-05-01 | PXD041905 | JPOST Repository
UnknownSARS-CoV-2 outbreak in Iran: The dynamics of the epidemic and evidence on two independent introductions.
Not available
S-EPMC8251331 | biostudies-literature
UnknownEvaluation of the effect of sofosbuvir and daclatasvir in hospitalized COVID-19 patients: a randomized double-blind clinical trial (DISCOVER).
Not available
S-EPMC8690191 | biostudies-literature
UnknownGlobal variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c.
Not available
S-EPMC10667106 | biostudies-literature
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