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ProteomicsStudy of peptides produced during proteasomal degradation of MBP (Myelin basic protein) and IGF-1 (insuline-like growth factor 1) in presence and absence of PA28γ
In vitro degradation of MBP and chemically denatureted IGF-1 by 20S and PA28γ-20S proteasomes and tandem mass spectrometry (MS/MS) qualitative and semi-quantitative analysis of the entire spectrum of peptides produced
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2024-01-24 | PXD029248 | Pride
Pa28γ  proteasome  proteasome activator  proteasome gate  protein degradation  atp-independent proteolysis 
ProteomicsATM interactome and analysis of its substrates
Study of ATM interactome and its substrates following pull-down with anti -pSQ/TQ antibody
ORGANISM(S): Homo sapiens (Human) 
2024-01-24 | PXD032194 | Pride
Nlc-ms-ms Phosphorylated proteins Interactome 
ProteomicsSEPN1-related myopathy depends on the oxidoreductase ERO1 alpha and is druggable with the chemical chaperone TUDCA
SEPN1-related myopathy depends on the oxidoreductase ERO1 alpha and is druggable with the chemical chaperone TUDCA
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD047157 | Pride
Tudca Multi mini-core disease Er stress Ero1 Sepn1 Core myopathy 
ProteomicsReplication stress primes a trophectoderm fate in embryonic stem cells
Early embryogenesis is marked by extremely rapid cell cycles that generate significant replication stress (RS), but how this stress influences cell-fate potential is not fully understood. Using mouse embryonic stem cells as a model of the inner cell mass, we show that RS quickly and persistently act...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD071534 | Pride
Dna replication stress Trophectoderm (te) Embryogenesis Chromatin proteomics Mass spectrometry (ms) Cancer development 
ProteomicsERO1 alpha deficiency increases N-glycosylation of a proangiogenic VEGFA by MAGT1-dependent OST complex
N-glycosylation and disulfide bond formation are two essential steps in protein folding, that both take place in the endoplasmic reticulum (ER). These two modifications can influence each other, but the exact timing, as well as the mediators of this important crosstalk, are still not completely eluc...
ORGANISM(S): Homo sapiens (Human) 
2022-08-29 | PXD033941 | Pride
Vegfa Ero1 alpha N-glycosylation Nlc-esi-ms/ms Oxidative folding 
ProteomicsProteomics of the astrocyte secretome
Proteomics of the astrocyte secretome in response to soluble oligomeric Aß
ORGANISM(S): Mus musculus (Mouse) 
2023-05-23 | PXD036343 | Pride
Mouse Lcmsms 
ProteomicsBACE2 and lipid metabolism (DMSO versus BACE2i 3I proteomic analysis)
proteomic analysis of melanoma, PDAC cells and fibroblast treated with DMSO vs 3I
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD058789 | Pride
Bace2 lipid metabolism 
ProteomicsBACE2 and lipid metabolism (spatial proteomics)
spatial proteomic analysis of malanoma IGR37 cell lines
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD058731 | Pride
Bace2 lipid metabolism 
ProteomicsBACE2 and lipid metabolism (SSO treatment plus BACE2i time couse proteomic analysis)
SSO treatment and BACe2i time couse proteomic analysis in melanoma IGR37 cell lines
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD058751 | Pride
Bace2 lipid metabolism 
ProteomicsBACE2 and lipid metabolism (global proteomic analysis)
global proteomic analysis of melanoma cell lines expressing different bace2 levels
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD058702 | Pride
Bace2 lipid metabolism cancer 
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