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TranscriptomicsTranscriptome of soleus muscle of Tenascin-C deficient 129/SV mice
1 year-old male Tenascin-C deficient 129/SV mice with the targeted insertion of a beta-lactamase cassette in the NcoI site of exon 2 of the TNC gene (Forsberg, E., Hirsch, E., Frohlich, L., Meyer, M., Ekblom, P., Aszodi, A., Werner, S. & Fassler, R. (1996) Proc. Natl. Acad. Sci U. S. A 93, 6594-6599...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-8550 | biostudies-arrayexpress
TranscriptomicsTranscriptome of reloaded soleus muscle of Tenascin-C deficient 129/SV mice
1 year-old male Tenascin-C deficient 129/SV mice with the targeted insertion of a beta-lactamase cassette in the NcoI site of exon 2 of the TNC gene (Forsberg, E., Hirsch, E., Frohlich, L., Meyer, M., Ekblom, P., Aszodi, A., Werner, S. & Fassler, R. (1996) Proc. Natl. Acad. Sci U. S. A 93, 6594-6599...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-8551 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of Foxi3 null embryonic back skin epithelium
Foxi3 is a transcription factor expressed in the hair follicle epithelium during development and postnatally. In this study we used a microarray analysis to indentify differentially expressed genes in Foxi3 null epithelium compared to Foxi3 wt epithelium. We used E15.5 stage as the earliest time poi...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-68985 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse back skin of wild type and Range knockout animals after aceton treatment.
In order to identify critical changes in the genetic network of Rage signaling induced by TPA throughout a 48 h kinetic, global gene expression analysis was performed. Total RNA from untreated, 24h acetone- and 6, 12, 24, 48 h TPA-treated wt and Rage KO back skin was prepared (n=3 independent animal...
ORGANISM(S): Mus musculus 
2010-11-29 | E-MTAB-205 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse back muscle from Six1-/-Six4-/- and control embryos in order to identify genes under the control of Six proteins at E18.5. E18.5
The aim of the experiment was to compare the transcriptome of Six1-/-Six4-/- and control embryos in order to identify genes under the control of Six proteins at E18.5. E18.5 RNAs from back muscles of three SixdKO and two control embryos were hybridized on Affymetrix mouse genome 430A2.0 arrays (Affy...
ORGANISM(S): Mus musculus 
2009-10-08 | E-MEXP-1848 | biostudies-arrayexpress
ProteomicsUbiquitin mediated intracellular trafficking is required for Jam-C function
Endothelial cells form a barrier between the components present in the blood and the underlying tissue. Essential to formation of this barrier are junctional complexes present between cells. These complexes are dynamic, tightly regulated and remodel during key physiological processes such as inflamm...
ORGANISM(S): Homo sapiens (Human) 
2019-11-06 | PXD013003 | Pride
Proteomics Intracellular trafficking Endothelial cells Jam-c Ubiquitin Lc-ms/ms 
TranscriptomicsOverexpression of c-Jun in mouse Schwann cells of uninjured nerves
Two mouse lines, OE/+ and OE/OE were generated expressing graded elevation (6 fold and 28 fold, respectively) of c-Jun protein selectively in Schwann cells. The effects of this on global gene expression and cellular structure in uninjured nerves was analysed during development and in the adult. Chan...
ORGANISM(S): Mus musculus 
2017-10-16 | E-MTAB-6138 | biostudies-arrayexpress
TranscriptomicsInhibition of beta-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing
We performed gene expression profiling of P1 and P5 back and tail dermis to uncover potential explanations for the differences in HF formation at different ages and in different body sites. To generate back and tail dermis microarray from P1 mouse (C57Bl6/CBA F1), tail skin was incubated in 5mM EDTA...
ORGANISM(S): Mus musculus 
2016-07-18 | E-GEOD-83117 | biostudies-arrayexpress
Transcriptomicssingle-cell RNA-seq of mouse back skin treated with TPA
Mice are cancer-prone, whereas naked mole-rats are cancer-resistant. To test the discrepancies between how mouse and naked mole-rat skin responds to carcinogens, we topically treated animals with DMBA followed by TPA. In this dataset, we additionally perform single-cell RNA-seq on back skin in mice ...
ORGANISM(S): Mus musculus 
2025-11-19 | E-MTAB-13556 | biostudies-arrayexpress
TranscriptomicsWhole exome sequencing grid of untreated, TPA-treated, and DMBA+TPA-treated mouse back skin
We generated meso-scale grids from mouse back skin by collecting paired whole-exome sequencing (WES) and bulk RNA sequencing (bulk RNA), retaining coordinate information to preserve spatial context across the grids. Grids were derived from untreated mice (UN, n = 4), mice treated with the cell-cycle...
ORGANISM(S): Mus musculus 
2026-06-11 | E-MTAB-15745 | biostudies-arrayexpress
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