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ProteomicsMechanical loading modulates AMPK and mTOR signaling in myoblasts
Skeletal muscle adaptation to exercise involves various phenotypic changes that enhance metabolic and contractile functions. One key regulator of these adaptive responses is the activation of AMPK, influenced by exercise intensity. However, the mechanistic understanding of AMPK activation during exe...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050925 | Pride
Lc-ms L6 muscle cells Mechanical loading 
ProteomicsThe influence of IL-1β and TNF-α on the tenogenic differentiation of human periodontal ligament stem cells via global proteomic analysis
The hPDLSCs were cultured in the tenogenic medium treated with 0.1 ng/ml IL-1β or 10 ng/ml TNF-α for 7 days. Total proteins were isolated from the collected cell samples. Subsequently, the LFQ-based proteomic analysis was conducted for the extracted proteins in each group as established procedures...
ORGANISM(S): Homo Sapiens 
2024-10-05 | PXD056585 |
ProteomicsThe data of protein expression of hMSCs in Soft, Medium and Stiff group
After treated with different stiffness and macrophage paracrine signals at the same stiffness for 3 days, MSCs were harvested for proteomic analysis. The label-free quantification (LFQ) based proteomic analysis was performed for global protein expressions.
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035511 |
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