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UnknownStructural and functional evidence of bacterial antiphage protection by Thoeris defense system via NAD+ degradation.
Not available
S-EPMC7272460 | biostudies-literature
UnknownBacterial Hachiman complex executes DNA cleavage for antiphage defense.
Not available
S-EPMC11914072 | biostudies-literature
UnknownDynamic control of bacterial antiphage defense through the CdnG-Cap5 cyclic oligonucleotide-based antiphage pathway in Vibrio cholerae.
Not available
S-EPMC12804361 | biostudies-literature
UnknownSystematic discovery of antiphage defense systems in the microbial pangenome.
Not available
S-EPMC6387622 | biostudies-literature
GenomicsTranscriptomics reveals the role of NHEJ in mycobacterial antiphage defense
Transcriptomics reveals the role of NHEJ in mycobacterial antiphage defense
PRJNA1395048 | ENA
ProteomicsDNA-intercalating antiphage molecules trigger abortive infection through ‘mutual destruction’ and synergize with bacterial immunity
Bacteria deploy diverse antiphage defense systems, including small bioactive molecules providing protection at the multicellular level. DNA-intercalating anthracyclines such as daunorubicin exhibit broad antiphage activity, but the underlying mechanism had remained elusive. Here, we systematically s...
ORGANISM(S): Escherichia coli Escherichia phage HildyBeyeler 
2026-05-13 | PXD070949 | Pride
T5-like phage E.coli 
UnknownResistance against aminoglycoside antibiotics via drug or target modification enables community-wide antiphage defense.
Not available
S-EPMC11350373 | biostudies-literature
TranscriptomicsTranscriptomics reveals the role of NHEJ in mycobacterial antiphage defense
In the ongoing arms race with phages, bacteria have evolved diverse defense systems, such as CRISPR-Cas and restriction-modification systems. The DNA double-strand break (DSB) repair system represents a core mechanism for maintaining genomic integrity and is vital for cell survival. However, it rema...
ORGANISM(S): Mycolicibacterium smegmatis 
2026-01-01 | GSE315142 | GEO
UnknownPhage nuclease-mediated defense activation of the bacterial Retron-Eco7 toxin-antitoxin system.
Not available
S-EPMC12640716 | biostudies-literature
UnknownMycobacterial non-homologous end joining is required for antiphage defense.
Not available
S-EPMC12848934 | biostudies-literature
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