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MetabolomicsComparative Transcriptome and Energy Metabolome Profiling Unravel the Key Role of GlcN6P Metabolic Pathway in Resistance against Bacteriophage in Enterotoxigenic Escherichia coli

The rapid emergence of phage-resistant bacterial mutants is a major challenge for phage application in the food industry. The resistance mechanisms of Enterotoxigenic E. coli (ETEC) against phage infection are largely unknown. In Escherichia coli, RapZ regulates gluc...

2025-12-15 | MTBLS13411 | MetaboLights
TranscriptomicsBiological characterization of virulent therapeutic bacteriophage PAK_P3 infecting Pseudomonas aeruginosa.
We have isolated and characterized several bacteriophages infecting Pseudomonas aeruginosa distantly related to Felix O1 virus and proposed they form a new subfamily named Felixounavirinae. The infectious cycle of bacteriophages belonging to this subfamily has not been studied yet in terms of gene e...
ORGANISM(S): Pseudomonas aeruginosa 
2016-07-20 | E-GEOD-76513 | biostudies-arrayexpress
TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
TranscriptomicsTime course of bacteriophage ?YS40 infection in wild-type and crp deletion Thermus thermophilus HB8 strain
This SuperSeries is composed of the following subset Series: GSE16954: Time course of the mRNA expression after bacteriophage ?YS40 infection in wild-type Thermus thermophilus HB8 strain. GSE16955: Time course of the mRNA expression after phage ?YS40 infection in crp deletion mutant of Thermus therm...
ORGANISM(S): Thermus thermophilus HB8 
2009-11-02 | E-GEOD-16978 | biostudies-arrayexpress
TranscriptomicsTime course of the mRNA expression after bacteriophage Ï•YS40 infection in wild-type Thermus thermophilus HB8 strain.
We observed the expression profile of the total mRNA of wild-type Thermus thermophilus HB8 strain during infection of bacteriophage ϕYS40. Keywords: time course, bacteriophage, infection, wild type Three wild-type T. thermophilus HB8 strains were pre-cultured at 70°C for 16 h in 3 ml of TT medium ...
ORGANISM(S): Thermus thermophilus HB8 
2010-06-20 | E-GEOD-16954 | biostudies-arrayexpress
GenomicsCharacterization of attB and core-attP recombination sites of the integrase from Lactobacilus delbrueckii subsp. bulgaricus bacteriophage mv4
Different attB or attP DNA libraries containing 7-bp random nucleotides were used for in vitro recombination mediated by the purified integrase from mv4 bacteriophage against their cognate wild-type attB or attP recombination site.
ORGANISM(S): Lactobacillus delbrueckii subsp. bulgaricus 
2023-12-10 | E-MTAB-13571 | biostudies-arrayexpress
GenomicsBacteriophage sp. strain:Klebsiella pneumoniae
Bacteriophage sp. strain:Klebsiella pneumoniae Genome sequencing
PRJNA643644 | ENA
TranscriptomicsTime course of the mRNA expression after phage ϕYS40 infection in crp deletion mutant of Thermus thermophilus HB8.
We observed the expression profile of the total mRNA in crp (TTHA1437) deletion mutant strain of Thermus thermophilus HB8 during infection of bacteriophage ϕYS40. Keywords: time course, bacteriophage, infection, CRP, cAMP receptor protein, deletion mutant Three crp (TTHA1437) delection mutant strain...
ORGANISM(S): Thermus thermophilus HB8 
2009-11-02 | E-GEOD-16955 | biostudies-arrayexpress
MetabolomicsTranscriptomic and Metabolomics Profiling of Phage–Host Interactions between Phage PaP1 and Pseudomonas aeruginosa
The basic biology of bacteriophage–host interactions has attracted increasing attention due to a renewed interest in the therapeutic potential of bacteriophages. In addition, knowledge of the host pathways inhibited by phage may provide clues to novel drug targets. However, the effect of phage on ba...
2018-05-03 | MTBLS431 | MetaboLights
TranscriptomicsHost intelligence in response to bacteriophage c2 infection in Lactococcus lactis IL1403
Bacteriophage infection of Lactococcus lactis strains used in the manufacture of fermented milk products is a major threat for the dairy industry. A greater understanding of the global molecular response of the bacterial host following phage infection has the potential to identify new targets for th...
ORGANISM(S): Lactococcus lactis 
2010-12-15 | E-GEOD-26042 | biostudies-arrayexpress
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