Ultra-high performance liquid chromatography-high resolution mass spectrometry (UPHLC-HRMS) is used to discover and monitor single or sets of biomarkers informing about metabolic processes of interest. The technique can detect thousands of molecules (i.e., metabolites) in a single instrument run ...
Despite remarkable advances in cancer genomics and targeted therapy, cholangiocarcinoma (CCA) is still one of the deadliest cancers. Current translational approaches have focused on genomic alterations, while leaving proteomic alterations, that may more directly pinpoint therapeutic targets, unexplo...
