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TranscriptomicsTrans-acting regulatory variation in Saccharomyces cerevisiae
Natural genetic variation can cause significant differences in gene expression, but little is known about the polymorphisms that affect gene regulation. We analyzed regulatory variation in a cross between laboratory and wild strains of Saccharomyces cerevisiae. Clustering and linkage analysis define...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-05 | E-GEOD-617 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of Saccharomyces cerevisiae to potassium starvation
In this study we investigated the transcriptional response of the yeast Saccharomyces cerevisiae to potassium starvation. To this end yeast cells were grown for 60 min in media without potassium or in media with a standard potassium concnetration (50 mM KCl). Using Serial Analysis of Gene Expressi...
ORGANISM(S): Saccharomyces cerevisiae 
2014-12-11 | E-GEOD-57093 | biostudies-arrayexpress
TranscriptomicsDisplacement and re-accumulation of centromeric cohesin during transient pre-anaphase centromere splitting
The ring-shaped cohesin complex links sister chromatids until their timely segregation during mitosis. Cohesin is enriched at centromeres, where it provides the cohesive counter-force to bi-polar tension produced by the mitotic spindle. As a consequence of spindle tension, centromeric sequences tran...
ORGANISM(S): Saccharomyces cerevisiae 
2007-09-29 | E-GEOD-8661 | biostudies-arrayexpress
TranscriptomicsA Myc transcriptional program that is independent of EMT drives a poor prognosis tumor-propagating phenotype in HER2+ breast cancer
The HER2 (ERBB2) and MYC genes are commonly amplified genes in breast cancer, yet little is known about their molecular and clinical interaction. Using a novel chimeric mammary transgenic approach and in vitro models, we demonstrate markedly increased self renewal and tumour propagating capability o...
ORGANISM(S): Homo sapiens 
2013-09-24 | E-GEOD-43730 | biostudies-arrayexpress
UnknownPhase I pharmacokinetic and pharmacodynamic study of the multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in pediatric relapsed/refractory leukemia.
Not available
S-EPMC3158600 | biostudies-literature
UnknownAssessment of stunned and viable myocardium using manganese-enhanced MRI.
Not available
S-EPMC8186753 | biostudies-literature
UnknownDetection, characterization, and enrollment of donors of Ebola convalescent plasma in Sierra Leone.
Not available
S-EPMC5947131 | biostudies-literature
UnknownManganese-Enhanced Magnetic Resonance Imaging in Takotsubo Syndrome.
Not available
S-EPMC7613919 | biostudies-literature
UnknownMultikinase Inhibitors Induce Cutaneous Toxicity through OAT6-Mediated Uptake and MAP3K7-Driven Cell Death.
Not available
S-EPMC4713045 | biostudies-literature
UnknownRandomised crossover trial of telemonitoring in chronic respiratory patients (TeleCRAFT trial).
Not available
S-EPMC4819626 | biostudies-literature
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