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MetabolomicsA metabolomics exploration of the sexual phase in the marine diatom Pseudo-nitzschia multistriata
Pseudo-nitzschia multistriata is a planktonic diatom species with a diplontic life cycle comprising a short sexual phase during which gametes are produced from the encounter of two diploid cells of opposite mating type (MT). Gene expression studies have highlighted the presence of substantial change...
2020-06-29 | MTBLS1714 | MetaboLights
TranscriptomicsTranscription profiling of Drosophila developmental time series
Michelle N. Arbeitman, Eileen E. M. Furlong, Farhad Imam, Eric Johnson, Brian H. Null, Bruce S. Baker, Mark A. Krasnow, Matthew P. Scott, Ronald W. Davis and Kevin P. White. Gene Expression During the Life Cycle of Drosophila melanogaster, Science, 297: 2270-2275, 2002. This work can be accessed fro...
ORGANISM(S): Drosophila melanogaster 
2004-11-06 | E-FLYC-6 | biostudies-arrayexpress
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
ProteomicsThe role of HnrnpF/H as a driver of Oligoteratozoospermia
Male subfertility or infertility is a common condition often characterized by men producing a low number of sperm with poor quality. To gain insight into this condition, we performed a quantitative proteomic analysis of semen samples obtained from infertile and fertile men.
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD046594 | Pride
Human Sperm Male infertility Swath-ms 
UnknownPhase IB Study of Selinexor, a First-in-Class Inhibitor of Nuclear Export, in Patients With Advanced Refractory Bone or Soft Tissue Sarcoma.
Not available
S-EPMC5321073 | biostudies-literature
TranscriptomicsEccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways
Full title: Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes. Unaccustomed eccentric exercise damages muscle tissue stimulating mechanisms of recovery and remodeling that may be affected by cellular protection by the sex...
ORGANISM(S): Homo sapiens 
2009-12-16 | E-GEOD-19062 | biostudies-arrayexpress
UnknownThe oral microbiome: diversity, biogeography and human health.
Not available
S-EPMC11084736 | biostudies-literature
ProteomicsPre- and Post- NACT ovarian cancer
Samples from 22 ovarian cancer patients before and again after neoadjuvant chemotherapy
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD070494 | Pride
Ovarian cancer Neoadjuvant chemotherapy 
ProteomicsPKA signaling network-quantitative proteomics and phosphoproteomics
Classically, connections within a complex network can be identified through systematically removing its components one at a time and observing the resulting functional changes throughout the network. We applied this concept to identify the signaling network downstream from protein kinase A (PKA) in...
ORGANISM(S): Mus musculus (Mouse) 
2017-11-23 | PXD005938 | Pride
Mouse Kindey Pka Proteomics Phosphorylation 
ProteomicsCRISPR-Cas9/phosphoproteomics identifies Myosin Light Chain Kinase dependent signaling in kidney epithelial cells
Prior studies have implicated myosin light chain kinase (MLCK) in the regulation of aqua-porin-2 (AQP2) in the renal collecting duct. To discover signaling targets of MLCK, we deleted the Mylk- gene to obtain MLCK-null mpkCCD cells and carried out comprehensive phosphopro-teomics using the SILAC met...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-04 | PXD014985 | Pride
Nuclear membrane Mass spectrometry Vasopressin Aqp2 Endosomal trafficking Sted microscopy 
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