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UnknownModeling the Population Health Impact of Introducing a Modified Risk Tobacco Product into the U.S. Market.
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S-EPMC6023310 | biostudies-literature
MetabolomicsMetabolic Changes of Maternal Uterine Fluid, Uterus, and Plasma during the Peri-implantation Period of Early Pregnancy in Mice
Embryo implantation is a complex process which involves biochemical and physiological interactions between an implantation-competent blastocyst and a receptive uterus. However, the exact biochemical changes of uterine fluid, uterus, and plasma during peri-implantation remain unclear. This study aims...
2020-05-04 | MTBLS627 | MetaboLights
ProteomicsSIRT1 binding proteins in human first trimester villi and HTR8/SVneo cells
In this study, we investigated the potential downstream target proteins in trophoblasts that were regulated by SIRT1 through modulation of acetylation. To this end, the IP products of SIRT1 in the lysate of human first-trimester villous tissue and HTR8/SVneo cells were subjected to proteomics analys...
ORGANISM(S): Homo Sapiens 
PXD026574 |
TranscriptomicsGene deletion expression profiles of yeast chromatin modifiers
Packaging of DNA into chromatin has a profound impact on gene expression. To understand how changes in chromatin influence transcription, we analyzed 165 mutants of chromatin machinery components in Saccharomyces cerevisiae. mRNA expression patterns change in 80% of mutants, always with specific eff...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-23 | E-GEOD-25909 | biostudies-arrayexpress
TranscriptomicsGene Expression Patterns in Peripheral Blood Mononuclear Cells Associated with Asthma Exacerbation Attack
A large, prospective, non-interventional study was designed to study gene expression changes in peripheral blood mononuclear cells (PBMCs) associated with asthma exacerbations over the course of a year. PBMC samples were collected from subjects at the time of the study visits defined as 1) Quiet: du...
ORGANISM(S): Homo sapiens 
2011-07-13 | E-GEOD-19301 | biostudies-arrayexpress
Transcriptomicsyeast wt-matA pool
Contains a collection of wildtype matA Saccharomyces cerevisiae strains for estimating the biological variation. Two channel microarrays were used. RNA isolated from a large amount of wt yeast from a single culture was used as a common reference. Two independent cultures were hybridized on two separ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-14 | E-GEOD-42240 | biostudies-arrayexpress
TranscriptomicsSlx5_Slx8_Genome_Stability
The Saccharomyces cerevisiae Slx5/8 complex is the founding member of a recently defined class of ubiquitin ligases (STUbLs) that target sumoylated substrates. Slx5/8 has been implicated in genome stability and transcription, but the precise contribution to these processes is not clear. To character...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-06 | E-GEOD-33929 | biostudies-arrayexpress
Transcriptomicsyeast wt pool
Contains a collection of wildtype Saccharomyces cerevisiae strains for estimating the biological variation. Wildtypes are obtained from the yeast wildtypes - wt pool background set HybSet, by randomly taking 100 wt vs. refpool (pooled wts) and 100 refpool vs. wt hybridizations Two channel microarray...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-14 | E-GEOD-42215 | biostudies-arrayexpress
TranscriptomicsTemporal analysis of physiological, metabolite and transcriptome responses during drought identifies distinct early and late phases in Arabidopsis
Water availability is the biggest single limitation on plant productivity worldwide. In Arabidopsis, adjustments to drought stress, involving changes in metabolism and gene expression drive increased drought tolerance and initiate diverse drought avoidance and escape responses. To address regulatory...
ORGANISM(S): Arabidopsis thaliana 
2016-02-29 | E-GEOD-65046 | biostudies-arrayexpress
TranscriptomicsKaplan2013: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II
Dynamic control of gene expression is crucial for most aspects of cell physiology and at its core is RNA polymerase II (RNAPII). Using 53 RNAPII point mutants, we generated a point mutant epistatic miniarray profile (pE-MAP) comprising ~60,000 quantitative genetic interactions in Saccharomyces cere...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-06 | E-GEOD-47429 | biostudies-arrayexpress
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