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TranscriptomicsTranscripts differentially expressed in healthy blood mDCs compared to healthy monocytes
To directly compare the SLE monocyte transcriptional program with that of blood mDC precursors, we purified lineage HLA-DRhighCD11chigh mDCs and CD14+ monocytes from the blood of five healthy donors. Their gene expression profiles were then compared to those of blood SLE monocytes. An unsupervised c...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-46913 | biostudies-arrayexpress
ProteomicsERK signaling promotes IKKepsilon expression and oncogenic functions in pancreatic cancer cells in association with TBK1
A variety of cancers utilize RAS-regulated signaling pathways to promote oncogenic phenotypes. A widely studied example is pancreatic cancer, where mutant KRAS signaling leads to activation of MEK/ERK kinases and downstream signaling which promotes oncogenic mechanisms, including cell proliferation....
ORGANISM(S): Homo sapiens (Human) 
2025-08-05 | PXD060883 | Pride
Erk Ikkepsilon Mapk Tbk1 Kras 
UnknownCytokinin transfer by a free-living mirid to <i>Nicotiana attenuata</i> recapitulates a strategy of endophytic insects.
Not available
S-EPMC6059766 | biostudies-literature
TranscriptomicsGenomic Fingerprints of DC Subsets in the Human Vaginal Mucosa, Skin, and Blood
Dendritic cells (DC) localize throughout the body, where they sense and capture invading pathogens to induce protective immune responses. Hence, harnessing the biology of tissue-resident DC is crucial for the rational design of vaccines against pathogens. Herein, we characterized the transcriptomes ...
ORGANISM(S): Homo sapiens 
2014-12-17 | E-GEOD-54480 | biostudies-arrayexpress
UnknownSex ratio of mirid populations shifts in response to hostplant co-infestation or altered cytokinin signaling .
Not available
S-EPMC5234700 | biostudies-literature
TranscriptomicsBDCA1+ mDCs and BDCA3+ mDCs stimulated with vaccines for 6 hr
The mechanisms by which vaccines interact with human APCs remain elusive. We applied systems biology to define the transcriptional programs induced in human DCs by pathogens, innate receptor ligands and vaccines. Upon exposing DCs to influenza, Salmonella enterica and Staphylococcus aureus, we built...
ORGANISM(S): Homo sapiens 
2014-10-22 | E-GEOD-56744 | biostudies-arrayexpress
UnknownThe high optical brightness of the BlueWalker 3 satellite.
Not available
S-EPMC10686822 | biostudies-literature
UnknownIncreasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study.
Not available
S-EPMC10113325 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
UnknownDimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10831058 | biostudies-literature
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