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TranscriptomicsBlood Transcriptional Profiles of Active TB (UK Test Set Separated)
This dataset aims to dissect the whole blood transcriptional signature by determining if elements of the whole blood signature are still present in purified cell subpopulations. We aimed to characterise the transcriptional response during TB and identify if cell subsets drove changes in whole blood ...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-19443 | biostudies-arrayexpress
TranscriptomicsBlood Transcriptional Profiles in Active and Latent Tuberculosis UK (Training Set)
The aim of the project was to define transcriptional signatures in whole blood of TB patients (before drug treatment) and healthy controls to distinguish the signature of Latent and Active TB patients from each other and from healthy controls. This will help in diagnosis of active tuberculosis which...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-19439 | biostudies-arrayexpress
TranscriptomicsBlood Transcriptional Profiles in Human Active and Latent Tuberculosis
This series regroups different datasets (training set, test set, validation set, longitudinal set, separated cell set) to identify and characterise a specific transcriptional signature for patients with active TB, distinct from patients with latent TB and healthy controls. The training set dataset w...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-19491 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD4+ T cell to identify differences between HIV-1 resistant and HIV-1 susceptible individuals
Understanding why some individual resist HIV-1 infection despite continued exposure is an important goal for vaccine development. We compared CD4+ T cell gene expression at baseline in HIV-1 resistant commercial sex-workers from Nairobi, Kenya to HIV-1 high-risk negative (non-resistant) commercial s...
ORGANISM(S): Homo sapiens 
2009-01-17 | E-GEOD-14278 | biostudies-arrayexpress
TranscriptomicsDNA Methylation of gDNA from blood and bronchoalveolar lavage of tuburbulosis patients with and without type 2 diabetes via Illumina Infinium MethylationEPIC array
Tuberculosis (TB) remains a leading cause of illness and death globally. Type 2 diabetes (T2D) patients are more likely to become infected with Mycobacterium tuberculosis (M.tb). When they are infected, they are more likely to develop active TB disease and to present with more severe TB and those wh...
ORGANISM(S): Homo sapiens 
2025-12-14 | E-MTAB-16151 | biostudies-arrayexpress
UnknownTongue swab <i>Mycobacterium tuberculosis</i> qPCR for community screening of asymptomatic TB vs. clinic-based triage of symptomatic TB.
Not available
S-EPMC12919145 | biostudies-literature
UnknownEndothelial Cells Promote Productive HIV Infection of Resting CD4+ T Cells by an Integrin-Mediated Cell Adhesion-Dependent Mechanism.
Not available
S-EPMC8861939 | biostudies-literature
UnknownEpitope mapping of HIV-specific CD8+ T cells in a cohort dominated by clade A1 infection.
Not available
S-EPMC2735720 | biostudies-literature
TranscriptomicsCataloguing of Potential HIV Susceptibility Factors during the Menstrual Cycle of Pigtail Macaques
Our earlier studies in pig-tailed macaques demonstrated varying SHIV susceptibility during the menstrual cycle, likely caused by cyclic variations in immune responses in the female genital tract. There is concern that high-dose, long-lasting, injectable progestin-based contraception could mimic the...
ORGANISM(S): Macaca nemestrina 
2015-07-08 | E-GEOD-68079 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
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