Sort   by:  
 Page size 
UnknownA policy-driven framework for conserving the best of Earth's remaining moist tropical forests.
Tropical forests vary in composition, structure and function such that not all forests have similar ecological value. This variability is caused by natural and anthropogenic disturbance regimes, which influence the ability of forests to support biodiversity, store carbon, mediate water yield and fac...
S-EPMC7529876 | biostudies-literature
UnknownCommon Genetic Variants Contribute to Risk of Transposition of the Great Arteries.

Rationale

Dextro-transposition of the great arteries (D-TGA) is a severe congenital heart defect which affects approximately 1 in 4,000 live births. While there are several reports of D-TGA patients with rare variants in individual genes, the majority of D-TGA cases remain genetically elusiv...
S-EPMC8768504 | biostudies-literature
UnknownPatterns of Oxygenation, Mortality, and Growth Status in the Surfactant Positive Pressure and Oxygen Trial Cohort.

Objective

To characterize actual achieved patterns of oxygenation in infants born appropriate vs small for gestational age (SGA) randomized to a lower (85-89%) vs higher (91%-95%) oxygen saturation target in the Surfactant Positive Pressure and Oxygen Trial. To determine the association betw...
S-EPMC5484739 | biostudies-literature
UnknownTarget ranges of oxygen saturation in extremely preterm infants.

Background

Previous studies have suggested that the incidence of retinopathy is lower in preterm infants with exposure to reduced levels of oxygenation than in those exposed to higher levels of oxygenation. However, it is unclear what range of oxygen saturation is appropriate to minimize ret...
S-EPMC2891970 | biostudies-literature
UnknownTitin-related familial dilated cardiomyopathy: factors associated with disease onset.

Background and aims

Truncating variants in the TTN gene (TTNtv) are the most common genetic cause of dilated cardiomyopathy (DCM) but also occur as incidental findings in the general population. This study investigated factors associated with the clinical manifestation of TTNtv.

Methods

S-EPMC12718689 | biostudies-literature
UnknownGlobal COVID-19 lockdown highlights humans as both threats and custodians of the environment.
The global lockdown to mitigate COVID-19 pandemic health risks has altered human interactions with nature. Here, we report immediate impacts of changes in human activities on wildlife and environmental threats during the early lockdown months of 2020, based on 877 qualitative reports and 332 quantit...
S-EPMC8135229 | biostudies-literature
UnknownPaCO2 in surfactant, positive pressure, and oxygenation randomised trial (SUPPORT).

Objective

To determine the association of arterial partial pressure of carbon dioxide PaCO2 with severe intraventricular haemorrhage (sIVH), bronchopulmonary dysplasia (BPD), and neurodevelopmental impairment (NDI) at 18-22 months in premature infants.

Design

Secondary exploratory dat...
S-EPMC4336211 | biostudies-literature
UnknownNeurodevelopmental outcomes in the early CPAP and pulse oximetry trial.

Background

Previous results from our trial of early treatment with continuous positive airway pressure (CPAP) versus early surfactant treatment in infants showed no significant difference in the outcome of death or bronchopulmonary dysplasia. A lower (vs. higher) target range of oxygen satur...
S-EPMC4140695 | biostudies-literature
UnknownGrowth Rates of Infants Randomized to Continuous Positive Airway Pressure or Intubation After Extremely Preterm Birth.

Objective

To evaluate the effects of early treatment with continuous positive airway pressure (CPAP) on nutritional intake and in-hospital growth rates of extremely preterm (EPT) infants.

Study design

EPT infants (240/7-276/7 weeks of gestation) enrolled in the S...
S-EPMC8478787 | biostudies-literature
UnknownEvaluating retinopathy of prematurity screening guidelines for 24- to 27-week gestational age infants.

Objective

To determine whether current retinopathy of prematurity (ROP) screening guidelines adequately identify treatable ROP in a contemporary cohort of extremely low gestation infants.

Study design

Data from the Surfactant, Positive Pressure, and Pulse Oximetry Randomized Trial wer...
S-EPMC3969774 | biostudies-literature
Sort   by:  
 Page size