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UnknownCarboplatin-associated ototoxicity in children with retinoblastoma.
Not available
S-EPMC3341147 | biostudies-literature
TranscriptomicsMiRNA expression in adipose tissue and liver from a spontaneous rat model of Type 2 diabetes
MicroRNAs (miRNAs) are non-coding RNA molecules involved in post-transcriptional control of gene expression of a wide number of genes, including those involved in glucose homeostasis. Type 2 diabetes (T2D) is characterized by hyperglycaemia and defects in insulin secretion and action at target tissu...
ORGANISM(S): Rattus norvegicus 
2010-05-16 | E-GEOD-17058 | biostudies-arrayexpress
TranscriptomicsVariability of gene expression profiles in human blood and lymphoblastoid cell lines
Readily accessible samples such as peripheral blood or cell lines are increasingly being used in large cohorts to characterise gene expression differences between a patient group and healthy controls. However, cell and RNA isolation procedures and the variety of cell types that make up whole blood c...
ORGANISM(S): Homo sapiens 
2011-07-25 | E-GEOD-30916 | biostudies-arrayexpress
MetabolomicsSex-specific effects of CD248 on metabolism and the adipose tissue lipidome

Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of Cd248. Strikingly, we find these to be sex speci...

2023-01-05 | MTBLS6615 | MetaboLights
TranscriptomicsTranscription profiling of human papillary serous ovarian adenocarcinomas and HUVEC and OVCA429 cells lines treated with recombinant MAGP2 - SuperSeries
This SuperSeries is composed of the following subset Series:; GSE18373: Expression data of HUVEC and OVCA429 with recombinant MAGP2; GSE18520: Whole-genome oligonucleotide expression analysis of papillary serous ovarian adenocarcinomas Experiment Overall Design: Refer to individual Series
ORGANISM(S): Homo sapiens 
2009-10-23 | E-GEOD-18521 | biostudies-arrayexpress
MetabolomicsMetabolomics identifies multiple candidate biomarkers to diagnose and stage human African trypanosomiasis
Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the disease (stage 1 defined by parasites being present in blood and lymphatics whilst for stage 2, parasites are found beyond the blood-brain barrier in the cerebrospinal flui...
2018-01-24 | MTBLS413 | MetaboLights
UnknownPediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop.
Not available
S-EPMC7383960 | biostudies-literature
TranscriptomicsTranscription profiling of mouse embryonic stem cells with a doxycycline-inducible Xist cDNA transgene introduced into chromosome 17
A doxycycline-inducible Xist cDNA transgene was introduced into mouse chromosome 17 at approximately 71.24Mb (NCBI Build m36). Insertion of the transgene was heterozygous, so only one copy of chromosome 17 carried the transgene, and the other chromosome 17 was wild-type. Upon doxycycline induction...
ORGANISM(S): Mus musculus 
2010-05-10 | E-MEXP-2087 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of homozygous Commd1 null mouse embryos to elucidate the underlying mechanism leading to embryonic lethality
A gene expression study using microarray analysis was performed to elucidate the underlying mechanism leading to embryonic lethality in homozygous Commd1 null (Commd1-/-) mouse embryos. A gene expression profile of 9.5 dpc Commd1-/- embryos were generated and were compared to a gene expression profi...
ORGANISM(S): Mus musculus 
2006-09-01 | E-MEXP-832 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cells with a doxycycline-inducible Xist cDNA transgene introduced into chromosome 3
A doxycycline-inducible Xist cDNA transgene was introduced into mouse chromosome 3 at approximately 99.79Mb (NCBI Build m36). Insertion of the transgene was homozygous, so only one copy of chromosome 3 carried the transgene, and the other chromosome 3 was wild-type. Upon doxycycline induction, the...
ORGANISM(S): Mus musculus 
2010-05-10 | E-MEXP-2086 | biostudies-arrayexpress
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