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UnknownRegulatory protein BBD18 of the lyme disease spirochete: essential role during tick acquisition?
Not available
S-EPMC3977360 | biostudies-literature
ProteomicsCoupled induction of prophage and virulence factors during tick transmission of the Lyme disease spirochete
The alternative sigma factor RpoS plays a central role in the critical host-adaptive response of the Lyme disease spirochete, Borrelia burgdorferi. We previously identified bbd18 as a negative regulator of RpoS but could not inactivate bbd18 in wild-type spirochetes. In the current study we employed...
ORGANISM(S): Borrelia burgdorferi B31 
2022-12-12 | PXD037736 | Pride
Borrelia burgdorferi Bbd18 Rpos 
TranscriptomicsCoupled induction of prophage and virulence factors during tick transmission of the Lyme disease spirochete
Lyme disease spirochetes must induce RpoS-dependent genes during tick feeding to prepare for host infection. Previous work in our lab identified bbd18 as a negative regulator of RpoS, but inactivation of bbd18 in wild-type spirochetes was never achieved. In the current study we generated an inducibl...
ORGANISM(S): Borreliella burgdorferi B31 
2022-12-12 | GSE207123 | GEO
UnknownCoupled induction of prophage and virulence factors during tick transmission of the Lyme disease spirochete.
Not available
S-EPMC9839762 | biostudies-literature
GenomicsCoupled induction of prophage and virulence factors during tick transmission of the Lyme disease spirochete
Coupled induction of prophage and virulence factors during tick transmission of the Lyme disease spirochete
PRJNA853762 | ENA
UnknownDksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity.
Not available
S-EPMC7924775 | biostudies-literature
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