Bead-based enrichment

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Proteomics (222)
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Neurodegeneration with brain iron accumulation 5 (1)

Technology Type

Mass Spectrometry (213)
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HDMSE (1)

Instrument Platform

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Liquid Chromatography MS - negative - reverse phase (2)
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Liquid Chromatography MS - positive - reverse-phase (1)

Publication Date

2025 (57)
2026 (36)
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2020 (15)
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2015 (11)
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2013 (9)
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2009 (1)

CHEBI ID

CHEBI:24168 (2)
CHEBI:17822 (2)
CHEBI:26271 (2)
CHEBI:17126 (2)
CHEBI:17505 (2)
CHEBI:18237 (2)
CHEBI:33508 (2)
CHEBI:16335 (2)
CHEBI:15756 (2)
CHEBI:134127 (1)
CHEBI:142346 (1)
CHEBI:138394 (1)
CHEBI:71049 (1)
CHEBI:38036 (1)
CHEBI:134612 (1)
CHEBI:16247 (1)
CHEBI:52057 (1)
CHEBI:136618 (1)
CHEBI:38460 (1)
CHEBI:144461 (1)
CHEBI:27890 (1)
CHEBI:17109 (1)
CHEBI:207013 (1)
CHEBI:199053 (1)
CHEBI:160829 (1)
CHEBI:138391 (1)
CHEBI:52350 (1)
CHEBI:188435 (1)
CHEBI:84755 (1)
CHEBI:81620 (1)

Metabolite Name

4-Pyridoxic acid (3)
Hydrocinnamic acid (2)
P-Toluenesulfonic acid (2)
Galactonic acid (2)
Diphenylamine (2)
Phenylacetaldehyde (2)
3-Hydroxyvaleric acid (2)
Folinic acid (2)
Kynurenic acid (2)
Trans-Cinnamic acid (2)
15-OxoEDE (2)
Pyridoxamine (2)
L-Histidine (2)
Deoxycholic acid (2)
Cholic acid (2)
Pimelic acid (2)
3-Hydroxybenzoic acid (2)
Stearic acid (2)
Pantothenic acid (2)
Undecanedioic acid (2)
Pipecolic acid (2)
Spermidine (2)
Suberic acid (2)
Azelaic acid (2)
Hippuric acid (2)
2-Monolinoleoylglycerol (1)
Monohexadecanoylglycerol (1)
Monopalmitoylglycerol (1)
W/o MS2:DAEFRHDSGYE/1 (1)
W/o MS2:3-GluA-28-Xyl(1-4)[Api(1-3)]Rha(1-2)Ara Medicagenic acid (1)

First Public Date

2024 (10)
2025 (5)
2021 (5)
2022 (4)
2013 (4)
2023 (3)
2020 (3)
2017 (2)
2016 (2)
2014 (2)
2026 (1)

Classification

bacteria (1)

Modification

N6 (1)
N6-dimethyl-L-lysine (1)

Study type

RNA-seq of coding RNA (14)
Transcription profiling by array (12)
ChIP-seq (7)
Other (5)
Methylation profiling by array (4)
RNA-seq of coding RNA from single cells (4)
RNA-seq of non coding RNA (3)
DNA-seq (2)
Methylation profiling by high throughput sequencing (2)
Transcription profiling by SAGE (1)
RNA-seq of non coding RNA from single cells (1)
ATAC-seq (1)
Hi-C (1)
Proteomic profiling by array (1)
CUT&RUN (1)

Release Date

2022 (21)
2024 (18)
2016 (13)
2015 (12)
2014 (12)
2020 (11)
2025 (11)
2017 (10)
2013 (9)
2021 (9)
2019 (9)
2023 (8)
2012 (7)
2026 (4)
2018 (4)
2011 (4)
2010 (4)
2009 (3)
2006 (2)
2007 (2)

Lab affiliation

Institute of Molecular Biology (IMB), Mainz, Germany (7)
ETH Zürich Institute of Molecular Systems Biology HPM F43 Otto-Stern-Weg 3 8093 Zürich Switzerland (5)
ETHZ IMSB (4)
Dr. Matthias Gstaiger ETH Zürich Institute of Molecular Systems Biology Otto-Stern-Weg 3 8093 Zürich Switzerland (3)
Ghent University, Department of Plant Biotechnology and Bioinformatics, Technologiepark 71, 9052 Ghent, Belgium VIB Center for Plant Systems Biology, Technologiepark 71, 9052 Ghent, Belgium (3)
Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland (3)
Aalborg University (2)
Amgen (2)
Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (2)
Basic Immune System of Plants / Protein Mass Spectrometry Max Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany (2)
Core Facility for Mass Spectrometry and Proteomics, Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany (2)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (2)
Department of Chemistry, Imperial College London, Exhibition Road, London SW7 2AZ, UK (2)
Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands. Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands. (2)
Dept. of Laboratory Medicine, University of California, San Francisco, CA (2)
Koç University, Department of Molecular Biology and Genetic Cell Biology Lab head (2)
Molecular Genetics, RPTU Kaiserslautern, Germany (2)
Nanoparticle Systems Engineering Laboratory Department of Mechanical and Process Engineering ETH Zurich, Switzerland (2)
Neuroproteomics DZNE Munich Feodor-Lynen-Str. 17 81377 Munich Germany (2)
Plant Physiology Group Westfälische WIlhelms-Universität Münster Germany (2)
Professor Laboratory Medicine and Pathology Mayo Clinic, Rochester, MN, USA (2)
1. Proteomics Unit of University of Bergen (PROBE), University of Bergen, Jonas Lies vei 91, 5009 Bergen, Norway 2 Department of Physical Chemistry, University of Granada, Avenida de la Fuente Nueva S/N, 18071 Granada, Spain 3 Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain (1)
1.Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, USA 2.Department of Microbiology, Harvard Medical School, Boston, MA, USA 3.Howard Hughes Medical Institute, Boston, MA, USA (1)
1Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands 2Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
1Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. (1)
Aalborg university (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University of Munich (TUM) Gregor-Mendel-Str. 4 85354 Freising Germany (1)
Biomedicine Discovery Institute, Monash University, Clayton, Australia. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia (1)
Boston College, Chemistry (1)
CECAD Research Center, Institute for Genetics, University of Cologne, 50931 Cologne, Germany (1)

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Bead-based kinase phosphorylation profiling identifies SRC as a therapeutic target in glioblastoma

Here we describe a bead-based method capable of profiling tyrosine kinase phosphorylations in a multiplexed, high-throughput and low-cost manner. This approach allows for the discovery of tyrosine kinase-activating events, even when the DNA sequence is wild-type. In an effort to pilot the establishm...

ORGANISM(S): Homo sapiens

2010-06-24 | E-GEOD-13808 | biostudies-arrayexpress

A magnetic bead-based workflow for sensitive and streamlined cell surface proteomics

Cell-surface proteins represent an important class of molecules for therapeutic targeting and defining cellular phenotypes. However, their enrichment and detection via mass spectrometry-based proteomics remains challenging due to low abundance, posttranslational modifications, hydrophobic regions, a...

ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse)

2024-01-21 | PXD043678 | Pride

Pre-analytical Sample Quality Determines Performance of Plasma Proteomics Workflows for Biomarker Discovery

This dataset contains mass spectrometry-based proteomic analyses of human plasma samples processed through five distinct proteomics workflows: neat plasma, perchloric acid precipitation with neutralization (PCA-N), and three bead-based enrichment methods (SAX magnetic beads, Sera Sil 700 magnetic be...

ORGANISM(S): Homo sapiens (Human)

2025-08-21 | PXD063572 | Pride

Pre-analytical variables Lc-ms Plasma proteomics Bead-based enrichment Cellular contamination Sample quality

Pre-analytical Sample Quality Determines Performance of Plasma Proteomics Workflows for Biomarker Discovery part02

ORGANISM(S): Homo sapiens (Human)

2025-08-21 | PXD063593 | Pride

Pre-analytical variables Lc-ms Plasma proteomics Bead-based enrichment Cellular contamination Sample quality

Proteome profiling of enriched lysosomes obtained from four commercial isolation methodologies.

Lysosomes are membrane-bound cell organelles that can be found in all mammalian cells. They contain digestive enzymes and are involved in multiple processes, including degradation of worn-out cell parts, antigen presentation and induction of programmed cell death. Mass spectrometry studies of lysoso...

ORGANISM(S): Homo sapiens (Human)

2026-02-23 | PXD040003 | Pride

Tmt Lysosome Sp3 Thp-1 Organelle enrichment

Evaluating Protein Enrichment Methods to Improve Biomarker Discovery in Equine Neurological Disorders

This study evaluated and compared three sample preparation strategies for proteomic analysis of equine cerebrospinal fluid (CSF): native in-solution digestion, the ProteoMiner™ Small-Capacity Enrichment Kit (Bio-Rad®), and the PreOmics Enrich-iST™ Kit (PreOmics®). CSF is in direct contact with the c...

ORGANISM(S): Equus caballus (Horse)

2026-04-13 | PXD063239 | Pride

Cerebrospinal fluid (csf) proteomics native digestion proteominer™ small-capacity enrichment kit preomics enrich-ist™ liquid chromatography with tandem mass spectrometry (lc-ms/ms)

HERVK HML-2 Target Enrichment Pilot

HERVK HML-2 Target Enrichment pilot experiment

PRJEB21477 | ENA

UltraPrep is a scalable, cost-effective, bead-based method for purifying cell-free DNA.

Not available

S-EPMC7263608 | biostudies-literature

Genomewide demarcation of RNA PolII transcription units by physical fractionation of chromatin- ORF-INT enrichment

Epigenetic modifications of chromatin serve an important role in regulating the expression and accessibility of genomic DNA. We report here a genomewide approach for fractionating yeast chromatin into two functionally distinct parts, one containing RNA polymerase II transcribed sequences, and the ot...

ORGANISM(S): Saccharomyces cerevisiae

2006-08-30 | E-GEOD-5650 | biostudies-arrayexpress

Validation of Flow Cytometry and Magnetic Bead-Based Methods to Enrich CNS Single Cell Suspensions for Quiescent Microglia.

Not available

S-EPMC4662612 | biostudies-literature

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