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ProteomicsReprograming of sRNA target specificity by the leader peptide peTrpL in response to antibiotic exposure
Trans-acting regulatory RNAs have the capacity to base pair with more mRNAs than experimentally detected under given conditions. This raises the question whether the sRNA target specificity can change upon metabolic or environmental changes. In Sinorhizobium meliloti, the sRNA rnTrpL is derived from...
ORGANISM(S): Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) 
2021-08-10 | PXD019516 | Pride
Small proteins Posttranscriptional regulation Attenuator Multiresistance Sinorhizobium meliloti Quantification 
UnknownAnatomical and Neuronal Distribution of the G-Coupled Protein Receptor 75 mRNA in the Mouse Central Nervous System.
Not available
S-EPMC12920073 | biostudies-literature
UnknownDifferent impact of bovine complement regulatory protein 46 (CD46bov) as a cellular receptor for members of the species Pestivirus H and Pestivirus G.
Not available
S-EPMC8741246 | biostudies-literature
ProteomicsThe leader peptide peTrpL forms antibiotic-containing ribonucleoprotein complexes for posttranscriptional regulation of multiresistance genes
Bacterial ribosome-dependent attenuators are widespread posttranscriptional regulators. They harbour small upstream ORFs (uORFs) encoding leader peptides, for which no functions in trans are known yet. In the soil-dwelling plant symbiont Sinorhizobium meliloti, the tryptophan biosynthesis gene trpE(...
ORGANISM(S): Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) 
2020-05-19 | PXD018342 | Pride
Small proteins Posttranscriptional regulation Attenuator Multiresistance Sinorhizobium meliloti Quantification 
ProteomicsIron regulation in Clostridioides difficile
The response to iron limitation of several bacteria is regulated by the ferric uptake regulator (Fur). The Fur-regulated transcriptional, translational and metabolic networks of the Gram-positive, pathogen Clostridioides difficile were investigated by a combined RNA sequencing, proteomic, metabolomi...
ORGANISM(S): Clostridioides difficile 050-P50-2011 
2019-01-11 | PXD011161 | Pride
Metabolism Fur Iron transport. cell wall Iron regulation Polyamine 
ProteomicsExoproteomes of S. aureus spa type t437 isolates
A total of 20 S. aureus spa type t437 isolates were used for exoproteome analyses in the present study. Ten of them were selected from MLVA type (MT) 621 group which has was shown to represent the most predominant class of S. aureus isolates with the spa type t437; the other ten isolates belonged to...
ORGANISM(S): Staphylococcus aureus 
2019-05-24 | PXD009082 | Pride
Staphylococcus aureus 
ProteomicsComparative exoproteome and virulence analysis of different clusters of Staphylococcus aureus with the Sequence Type ST398
Livestock-associated (LA) methicillin-resistant Staphylococcus aureus (MRSA) and strains of sequence type 398 (ST398), which first became known for its widespread colonization of pigs but are now also rapidly emerging in the number of human colonization and infections. The ability of broad host adap...
ORGANISM(S): Staphylococcus aureus 
2020-08-05 | PXD013951 | Pride
Virulence Methicillin-resistant staphylococcus aureus (mrsa) Mobile genetic elements (mge) Extracellular proteome Label-free quantitative mass spectrometry 
OtherComprehensive proteome analysis of Actinoplanes sp. SE50/110 highlighting the location of proteins encoded by the acarbose and the pyochelin biosynthesis gene cluster.
Data from ProteomeXchange, PXD ID: PXD001497. Experiment: SW_Exo_G2, file: 130519_o3_p4_ao_SW_Exo_G2_8.mzml. Published as part of J Proteomics. 2015 Jul 1;125:1-16 . From the Abstract: {{i}} Acarbose is an α-glucosidase inhibitor produced by Actinoplanes sp. SE50/110 that is medically importan...
ORGANISM(S): Actinoplanes_sp_se50_110 
GPM32320019694 | GPMDB
Resource Reanalysis 
ProteomicsProteomic Adaptation of Clostridioides difficile to Treatment with the Antimicrobial Peptide Nisin
Clostridioides difficile is the leading cause of antibiotics-associated diarrhea but can also result in more serious, life-threatening conditions. As incidence of C. difficile infections in hospitals is increasing, both in frequency and severity, and antibiotic-resistant C. difficile strains are adv...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2021-02-18 | PXD021684 | Pride
Nisin C. difficile Proteomics Mass spectrometry Antimicrobial peptides Antibiotic resistance 
ProteomicsVirulence induction in Pseudomonas aeruginosa under inorganic phosphate limitation: a proteomics perspective
Inorganic phosphate (Pi) is a central nutrient and signal molecule for bacteria. Pi limitation was shown to increase the virulence of a number of phylogenetically diverse pathogenic bacteria with different in lifestyles. Hypophosphatemia enhances the risk of death in patients due to general bacterem...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2022-11-02 | PXD033250 | Pride
Anti-infective therapy Proteomics Virulence Pseudomonas aeruginosa Pyocyanin Phosphate starvation Quorum sensing 
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