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TranscriptomicsTranscriptional landscape of transkingdom communication between Candida albicans and Streptococcus gordonii
Recent studies have shown that the transcriptional landscape of the pleiomorphic fungus Candida albicans is highly dependent upon growth conditions. Here using a dual RNA-seq approach we identified 299 C. albicans and 72 Streptococcus gordonii genes that were either up- or down-regulated specificall...
ORGANISM(S): Candida albicans 
2015-06-22 | E-GEOD-68477 | biostudies-arrayexpress
TranscriptomicsRNA-seq of EBVwt or EBVmutant infected human primary B cells on day 1, 2, 3, and 4 post-infection
Epstein-Barr virus (EBV) is a herpes virus that primarily infects, activates and immortalizes resting human B cells in vitro. EBNA2, a viral protein, is essential for the immortalization process because it transactivates a plethora of viral and cellular genes by interacting with the cellular DNA bi...
ORGANISM(S): Homo sapiens 
2022-07-04 | E-MTAB-11350 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of response to selenite of yeast strains that are wild type or deleted for transcription factor encoding genes involved in stress responses
This work aimed at analysing the transcriptome response of S. cerevisiae strains, wild type or deleted for transcription factor encoding genes involved in stress response, to selenite (1mM), inoculated for different time periods.
ORGANISM(S): Saccharomyces cerevisiae 
2008-03-14 | E-TABM-439 | biostudies-arrayexpress
GenomicsGenome-wide analysis reveals that budding yeast Rif1 binds to replication origins and at blocked replication forks to protect nascent DNA
This experiment details ChIP sequencing to decipher the binding sites of the Rif1 protein in budding yeast. Rif1 binds most strongly to telomeres where its binding is mediated by Rap1. To reduce telomere binding and help reveal Rap1-independent binding sites, a truncation mutant of Rif1 lacking the ...
ORGANISM(S): Saccharomyces cerevisiae 
2018-12-31 | E-MTAB-6736 | biostudies-arrayexpress
TranscriptomicsEffect of AICAr and SAICAr accumulation on global transcription in the ade3 mutant
We investigated the effects of AICAr and SAICAr accumulation on the global transcriptome of yeast, comparing the ade3 mutant to the WT strain. The ade3 mutant strain (Y4143) was compared to the WT strain (Y2946). For each comparison, we made 2 technical replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29021 | biostudies-arrayexpress
TranscriptomicsRole of Ado1p in the transcriptional response associated with AICAr supplementation
We investigated the role of Ado1p associated with AICAr supplementation on the global transcriptome of Y3188. The Y3188 strain was grown with or without AICAr. For each comparison, we made 2 biological replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29020 | biostudies-arrayexpress
GenomicsIdentification of Elg1 interaction partners and effects on post-replication chromatin re-formation
Elg1, the major subunit of a Replication Factor C-like complex, is critical to ensure genomic stability during DNA replication, and is implicated in controlling chromatin structure. We investigated the consequences of Elg1 loss for the dynamics of chromatin re-formation following DNA replication. Me...
ORGANISM(S): Saccharomyces cerevisiae 
2018-10-31 | E-MTAB-6985 | biostudies-arrayexpress
TranscriptomicsEffect of 5-amino-4-imidazolecarboxamide ribotide (AICAr) supplementation on global transcription
We investigated the effects of AICAr supplementation on the global transcriptome of Y2950. The Y2950 strain was grown with or without AICAr. For each comparison, we made 2 biological replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29019 | biostudies-arrayexpress
TranscriptomicsEffects of SFP1 deletion and Sfp1p prionization on transcription in Saccharomyces cerevisiae
Sfp1p is known to form the [ISP+] prion in Saccharomyces cerevisiae. Interestingly enough, the consequences and phenotypes of Sfp1p prionization and its absence are quite different. In order to understand the origin of this difference, we compared transcription profiles of an [ISP+], sfp1delta strai...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-23 | E-GEOD-52189 | biostudies-arrayexpress
GenomicsSWI/SNF and the histone chaperone Rtt106 drive expression of the Pleiotropic Drug Resistance network genes
Genome-wide binding of the histone chaperone Rtt106 was analysed by ChIP-seq. Rtt106 binding was analysed in WT and the mutant backgrounds lacking transcription factors Pdr1 and Pdr3, the HIR histone chaperone subunit Hir1, or the boundary protein Yta7. Two biological replicates had been submitted. ...
ORGANISM(S): Saccharomyces cerevisiae 
2022-02-21 | E-MTAB-9787 | biostudies-arrayexpress
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