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TranscriptomicsDifferential gene expression in cartilage from the mouse DMM osteoarthritis model
Transcriptional profiling of mouse cartilage comparing destabilised medial meniscal operated knee joints to sham operated knee joints in both wild type C57Bl/6 and C57Bl/6 ADAMTS5Dcat mice at 1, 2 and 6 weeks post DMM surgery. The goal was to determine the differential gene expression with the onset...
ORGANISM(S): Mus musculus 
2013-04-11 | E-GEOD-45793 | biostudies-arrayexpress
TranscriptomicsRNAseq of tumor samples from CT26 syngeneic mouse treated with a PD-L1 and CTLA-4 immunotherapy combination
The ability to modulate immune-inhibitory pathways using checkpoint blockade antibodies such as PD-1, PD-L1, and CTLA-4 represents a significant breakthrough in cancer therapy in recent years. This has driven interest in identifying small-molecule-immunotherapy combinations to increase the proportio...
ORGANISM(S): Mus musculus 
2020-04-16 | E-MTAB-7777 | biostudies-arrayexpress
UnknownSex Differences in the Association of Pretransfusion Hemoglobin Levels with Brain Structure and Function in the Preterm Infant.
Not available
S-EPMC9088851 | biostudies-literature
ProteomicsThe effect of polyethylene glycol 20,000 on protein extraction efficiency of formalin-fixed, paraffin-embedded tissues
The optimal conditions and procedures for efficient and reproducible protein extraction of FFPE tissues have not yet been standardised and new sensitive techniques are continually being developed and improved upon. To our knowledge, there is no general agreement as to the choice of detergent or buff...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD014419 | Pride
Archival tissue Protein extraction 000 Peg-20 Sp3-on-bead-digestion Ffpe proteomics Mass spectrometry 
ProteomicsEvaluation of protein purification techniques and effects of storage duration on LC-MS/MS analysis of archived FFPE human CRC tissues
To elucidate cancer pathogenesis and its mechanisms at the molecular level, the collecting and characterisation of large individual patient tissue cohorts are required. Since most pathology institutes routinely preserve biopsy tissues by standardised methods of formalin fixation and paraffin embedme...
ORGANISM(S): Homo sapiens (Human) 
2021-04-06 | PXD017198 | Pride
Human Label-free shotgun mass spectrometry Ffpe Colon cancer Protein purification Archival storage Colorectal cancer 
UnknownPrecision Population Medicine in Primary Care: The Sanford Chip Experience.
Not available
S-EPMC7994529 | biostudies-literature
Unknown31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts : National Harbor, MD, USA. 9-13 November 2016
Not available
S-EPMC5260784 | biostudies-literature
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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