Sort   by:  
 Page size 
UnknownTaccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.
Not available
S-EPMC3839246 | biostudies-literature
UnknownThe antibacterial cell division inhibitor PC190723 is an FtsZ polymer-stabilizing agent that induces filament assembly and condensation.
Not available
S-EPMC2863232 | biostudies-literature
UnknownHealthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway: A cohort study using OpenSAFELY-TPP.
Not available
S-EPMC10414967 | biostudies-literature
ProteomicsIn vivo Mapping of the Mouse Galnt3-specific O-Glycoproteome
The UDP-N-acetylgalactosamine polypeptide:N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes initiates O-linked glycosylation by catalyzing the addition of the first GalNAc sugar to serine or threonine on proteins destined to be membrane-bound or secreted. Defects in individual isoforms ...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD052978 | Pride
Mass spectrometry Galnac-t  galnt  glycopeptides  glycosyltransferase  hyperphosphatemic familial tumoral calcinosis (hftc)  o-galnac  o-glycosylation 
UnknownExperimental evolution of gallium resistance in Escherichia coli.
Not available
S-EPMC6928379 | biostudies-literature
ProteomicsNeuronal aging leads to disrupted RNA metabolism
Aging is one of the most prominent risk factors for neurodegeneration, yet the molecular mechanisms underlying the deterioration of old neurons are mostly unknown. To efficiently study neurodegeneration in the context of aging, we transdifferentiated primary human fibroblasts from aged (i.e. >50 yea...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD055826 | Pride
Human Neuron Transdifferentiation 
ProteomicsNeuronal aging leads to disrupted RNA metabolism
Aging is one of the most prominent risk factors for neurodegeneration, yet the molecular mechanisms underlying the deterioration of old neurons are mostly unknown. To efficiently study neurodegeneration in the context of aging, we transdifferentiated primary human fibroblasts from aged (i.e. >50 yea...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD055900 | Pride
Human Neuron Transdifferentiation 
ProteomicsFunctional analysis of a gene-edited mouse to gain insights into the disease mechanisms of a TITIN missense variant
Aims: Pathogenic truncating variants in the largest human protein TITIN are a leading cause of dilated cardiomyopathy. Because of the size of the gene encoding TITIN, many missense variations are identified. These are difficult to evaluate in genetic testing, as even individually rare variants are c...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-01 | PXD020390 | Pride
Proteomics Proteo-toxic response Telethonin Mouse model Proteasome Titin missense variant Cardiomyopathy 
UnknownAre Cal/OSHA Regulations Protecting Farmworkers in California From Heat-Related Illness?
Not available
S-EPMC8893044 | biostudies-literature
UnknownVariability in intensively assessed mood: Systematic sources and factor structure in outpatients with opioid use disorder.
Not available
S-EPMC10066936 | biostudies-literature
Sort   by:  
 Page size