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TranscriptomicsRNA-seq analysis of barley hvcbp20.ab, hvcbp80.b and hvcbp20.ab/hvcbp80.b under optimal conditions
Drought poses a significant limitation to crop yield. The nuclear Cap Binding Complex (CBC), made up of CBP20 and CBP80, plays a key role in regulating pre-mRNA splicing and abscisic acid (ABA) signaling. In this study, we examined how mutations in the barley CBC genes (hvcbp20.ab, hvcbp80.b, and th...
ORGANISM(S): Hordeum vulgare 
2025-12-31 | E-MTAB-15043 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of barley (Hordeum vulgare) single mutants in genes encoding barley CBC (HvCBP20, HvCBP80) and a double mutant in both genes encoding barley CBC in response to drought stress applied at the booting stage and subsequent rewatering
Drought poses a significant limitation to crop yield. The nuclear Cap Binding Complex (CBC), made up of CBP20 and CBP80, plays a key role in regulating pre-mRNA splicing and abscisic acid (ABA) signaling. In this study, we examined how mutations in the barley CBC genes (hvcbp20.ab, hvcbp80.b, and th...
ORGANISM(S): Hordeum vulgare 
2026-01-31 | E-MTAB-15052 | biostudies-arrayexpress
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in severe COVID19 patients
Memory B cells play a fundamental role in host defences against viruses. This dataset aimed at understanding their maturation and stability in the context of SARS-CoV-2 infection and consist of a longitudinal single-cell and repertoire profiling of the B cell response up to six months in four severe...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-9995 | biostudies-arrayexpress
MetabolomicsTaANT11-4A Enhances Grain Yield by Orchestrating Photosynthesis and Carbohydrate Metabolism through Direct Transcriptional Activation

Photosynthesis and carbohydrate metabolism are crucial for plant growth and yield. Given that the overexpression of TaANT11-4A not only increases grain size and weight in wheat but also enhances overall biomass, we hypothesize that TaANT11-4A may strengthen photosynthesis in source organs, thereb...

2026-10-08 | MTBLS15947 | MetaboLights
MetabolomicsMultiomics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites
Glandular trichomes are metabolic cell factories with the capacity to produce large quantities of secondary metabolites. Little is known about the connection between central carbon metabolism and metabolic productivity for secondary metabolites in glandular trichomes. To address this gap in our know...
2017-04-25 | MTBLS297 | MetaboLights
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in mRNA vaccinated individuals post BA.1-breakthrough infection
Memory B cells play a fundamental role in host defenses against viruses. This dataset aimed at understanding the recruitment and remodeling of the memory B cell repertoire in the context of BA.1-breakthrough infection in BNT162b2 mRNA vaccinated individuals. All four donors enrolled in the study had...
ORGANISM(S): Homo sapiens 
2023-08-15 | E-MTAB-12651 | biostudies-arrayexpress
GenomicsEssential role of the transcription factors E2A and E2-2 in germinal center B cell and plasma cell development
E2A is an essential regulator of early B-cell development. Here we demonstrated that E2A together with E2-2 controlled germinal-center B-cell and plasma cell development. As shown by identification of regulated E2A,E2-2 targets in activated B-cells, these E-proteins directly activated genes with imp...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-77744 | biostudies-arrayexpress
TranscriptomicsA missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency (Family B)
Affymetrix 6.0 SNP data for haplotype comparison of patients from two different families sharing the same homozygous mutation in TFRC, to determine if the families were related to each other Peripheral blood was used for patients who had no history of hematopoietic stem cell transplant (HSCT). Fibro...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75349 | biostudies-arrayexpress
UnknownLong-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin.
Not available
S-EPMC3515768 | biostudies-literature
MetabolomicsMetabolomic Responses of Guard Cells and Mesophyll Cells to Bicarbonate
Anthropogenic CO2 presently at 400 ppm is expected to reach 550 ppm in 2050, an increment expected to affect plant growth and productivity. Paired stomatal guard cells (GCs) are the gate-way for water, CO2, and pathogen, while mesophyll cells (MCs) represent the bulk cell-type of green leaves mainly...
2017-03-31 | MTBLS309 | MetaboLights
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