Sort   by:  
 Page size 
TranscriptomicsCENP-B cooperates with Set1 in bidirectional transcriptional silencing and genome organization of retrotransposons
Expression profiling of mutant cells compared to wild-type cells. Expression profiling of S. pombe CENP-B homolog cbp1M-bM-^HM-^F (abp1/SPBC1105.04c) and histone deacetylase double mutant clr3M-bM-^HM-^FM-BM- clr6-1 (SPBC800.03 SPBC36.05c) cells. Wildtype and mutant cDNA was reverse transcribed from...
ORGANISM(S): Schizosaccharomyces pombe 
2012-10-12 | E-GEOD-39404 | biostudies-arrayexpress
TranscriptomicsIdentification of miRNAs regulated by TGF-b in human CD8+ T cells (expression)
The goal of the current study was to identify miRNAs regulated by TGF-b in human CD8+ T cells and analyze the function of these miRNAs in shaping the immunomodulatory effect of TGF-b in these cells. We identified the miR-23a cluster to be upregulated and found that this cluster could target key mole...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-46324 | biostudies-arrayexpress
TranscriptomicsThe Nuclear Immune Receptor RPS4 Is Required for RRS1SLH1-Dependent Constitutive Defense Activation in Arabidopsis thaliana.
Plant nucleotide-binding leucine-rich repeat (NB-LRR) disease resistance (R) proteins recognize specific M-bM-^@M-^\avirulentM-bM-^@M-^] pathogen effectors and activate immune responses. NB-LRR proteins structurally and functionally resemble mammalian Nod-like receptors (NLRs). How NB-LRR and NLR pr...
ORGANISM(S): Arabidopsis thaliana 
2014-11-21 | E-GEOD-51116 | biostudies-arrayexpress
TranscriptomicsHistone acetylation and DNA demethylation of T-cells result in an anaplastic large cell lymphoma-like phenotype.
A characteristic feature of anaplastic large cell lymphoma (ALCL) is the significant reduction of the T-cell expression program despite its T-cell origin, a finding very similar to the loss of B-cell identity of classical Hodgkin lymphoma (cHL). Previously we demonstrated that epigenetic mechanisms ...
ORGANISM(S): Homo sapiens 
2012-08-19 | E-GEOD-26101 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of yeast to preferred and non-preferred nitrogen sources in C-lim chemostat cultures
Aerobic, glucose-limited chemostat cultures of Saccharomyces cerevisiae grown with six different nitrogen sources were subjected to transcriptome analysis. The use of chemostats enabled an analysis of nitrogen-source-dependent transcriptional regulation at a fixed specific growth rate. A selection o...
ORGANISM(S): Saccharomyces cerevisiae 
2007-02-28 | E-GEOD-6405 | biostudies-arrayexpress
TranscriptomicsEXPRSS: an Illumina based high-throughput expression-profiling method to reveal transcriptional dynamics - III
Background Next Generation Sequencing technologies have facilitated differential gene expression analysis through RNA-seq and Tag-seq methods. RNA-seq has biases associated with transcript lengths, lacks uniform coverage of regions in mRNA and requires 10M-bM-^@M-^S20 times more reads than a typical...
ORGANISM(S): Arabidopsis thaliana 
2014-06-20 | E-GEOD-52596 | biostudies-arrayexpress
TranscriptomicsFunctional characterization of a P. chrysogenum mutanase identified by co-cultivation with Bacillus subtilis.
Background: Microbial gene expression is to a large extend determined by environmental growth conditions. Differential gene expression analysis between two conditions has been frequently used to reveal regulatory networks and to assign physiological function to unknown genes. In nature, microorganis...
ORGANISM(S): Penicillium chrysogenum 
2014-05-12 | E-GEOD-53286 | biostudies-arrayexpress
TranscriptomicsMethylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines
DNA from Epstein-Barr virus (EBV)-transformed lymphocyte cell lines (LCLs) has proven very useful for studies of genetic sequence polymorphisms. Whether EBV-LCL DNA is suitable for methylation studies is less clear. We conduct a genome-wide methylation investigation using an array set with 45 millio...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-35204 | biostudies-arrayexpress
TranscriptomicsTemperature-dependent transcriptional response under anaerobic C and N limitations in Yeast
The global transcriptional response of Saccharomyces cerevisiae was investigated in low temperature chemostat cultures grown in carbon or nitrogen limitation. During steady state chemostats, the growth rates and in vivo fluxes were kept constant however the growth-limiting nutrient was significantly...
ORGANISM(S): Saccharomyces cerevisiae 
2007-01-20 | E-GEOD-6190 | biostudies-arrayexpress
TranscriptomicsExpression profiling during arabidopsis/downy mildew interaction reveals a highly-expressed effector that attenuates responses to salicylic acid.
Plants have evolved strong innate immunity mechanisms, but successful pathogens evade or suppress plant immunity via effectors delivered into the plant cell. Hyaloperonospora arabidopsidis (Hpa) causes downy mildew on Arabidopsis thaliana, and a genome sequence is available for isolate Emoy2. Here, ...
ORGANISM(S): Arabidopsis thaliana 
2014-11-21 | E-GEOD-53641 | biostudies-arrayexpress
Sort   by:  
 Page size