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TranscriptomicsMolecular Signatures of Neurogenesis in the Hippocampal Subgranular Zone of Rodents
We sought to find molecular signatures of the SGZ cell types, and to characterize the molecular pathways and transcription factor cascades that define the neurogenic niche. We used laser capture microdissection and DNA microarrays to profile gene expression in the inner (SGZ) and outer portions of t...
ORGANISM(S): Mus musculus 
2013-12-04 | E-GEOD-39697 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human leukocytes or whole blood isolated from burn/trauma subjects using either buffy coat or PAXgene methods
#G017 Burn/Trauma Study. This is a Glue Grant Study comparison between gene expression analyses performed in eight trauma/burn subjects using either a buffy coat isolation of whole blood or using the PAXgene system
ORGANISM(S): Homo sapiens 
2007-07-28 | E-GEOD-1343 | biostudies-arrayexpress
TranscriptomicsBlood RNA from metastatic Clear Cell Renal Carcinoma patients before or after treatment with nivolumab
Blood samples obtained at Cycle 1 Day 1, Cycle 1 Day 2 or at Cycle 2 Day 8 (i.e. before treatment, 24 hours after treatment or Week 4) from metastatic clear cell RCC patients treated with 0.2mpk, 3mpk or 10mpk (as 2nd or further line of therapy; Arms A,B,C) or 10mpk (as first line therapy; Arm D) of...
ORGANISM(S): Homo sapiens 
2016-05-15 | E-MTAB-3219 | biostudies-arrayexpress
ProteomicsInsights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis
Pulmonary alveolar microlithiasis is an autosomal recessive lung disease caused by a deficiency in the pulmonary epithelial Npt2b sodium-phosphate co-transporter that results in accumulation of phosphate and formation of hydroxyapatite microliths in the alveolar space. The single cell transcriptomic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-16 | MSV000091302 | MassIVE
TranscriptomicsBiopsies from metastatic Clear Cell Renal Carcinoma before or after treatment with nivolumab
Tumor core needle biopsies from kidney or metastatic sites obtained at trial enrollment i.e. Screen and/or at Cycle 2 Day 8 (i.e.Week 4) from metastatic clear cell RCC patients treated with 0.2mpk, 3mpk or 10mpk (as 2nd or further line of therapy; Arms A,B,C) or 10mpk (as first line therapy; Arm D) ...
ORGANISM(S): Homo sapiens 
2016-05-15 | E-MTAB-3218 | biostudies-arrayexpress
TranscriptomicsA genomic storm in critically injured humans
Human survival from injury requires an appropriate inflammatory and immune response. We describe the circulating leukocyte transcriptome after severe trauma and show that the severe stress produce a global reprioritization affecting >80% of the cellular functions and pathways, a truly unexpected “ge...
ORGANISM(S): Homo sapiens 
2012-03-26 | E-GEOD-36809 | biostudies-arrayexpress
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