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Hundreds of cytotoxic natural or synthetic lipidic compounds contain chiral alkynylcarbinol motifs, but the mechanism of action of those potential therapeutic agents remains unknown. Using a genetic screen in haploid human cells, we discovered that the enantiospecific cytotoxicity of numerous termin...
ORGANISM(S): Homo sapiens (Human) 
2022-05-10 | PXD033059 | Pride
We performed a microarray analysis to compare the expression profile of azurin treated and untreated with different P-cadherin expression levels. We also compared the differentially expressed genes regulated by P-cadherin overexpression. Both cell lines presented an up-regulation of apoptosis mediat...
ORGANISM(S): Homo sapiens 
We describe here the proteome of mouse embryonic stem cells growth in complete media (KSR, LIF/2i) or media without 2i for 24h and 48h.
ORGANISM(S): Mus musculus (Mouse) 
2025-06-23 | PXD033005 | Pride
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