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TranscriptomicsAffymetrix 250K StyI SNP array data for gastric and esophageal adenocarcinoma cancer types
Using data from high-density genomic profiling arrays, we describe the profiles of somatic copy-number aberrations (SCNAs) in 486 adenocarcinomas across all three major digestive organs, including 296 gastric and esophageal cancers. This analysis revealed that although patterns of broad, chromosome ...
ORGANISM(S): Homo sapiens 
2012-09-04 | E-GEOD-36459 | biostudies-arrayexpress
TranscriptomicsGenotyping of human glioma - assessing the significance of chromosomal aberrations in cancer
Comprehensive knowledge of the genomic alterations that underlie cancer is a critical foundation for diagnostics, prognostics and targeted therapeutics. Systematic efforts to analyze cancer genomes are underway, but the analysis is hampered by the lack of a statistical framework to distinguish mean...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-9635 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP 6.0 array data for colon, gastric and esophageal adenocarcinoma cancer types
Using data from high-density genomic profiling arrays, we describe the profiles of somatic copy-number aberrations (SCNAs) in 486 adenocarcinomas across all three major digestive organs, including 296 gastric and esophageal cancers. This analysis revealed that although patterns of broad, chromosome ...
ORGANISM(S): Homo sapiens 
2012-09-04 | E-GEOD-36458 | biostudies-arrayexpress
TranscriptomicsGastrointestinal Adenocarcinomas of the Esophagus, Stomach, and Colon Exhibit Distinct Patterns of Genome Instability and Oncogenesis.
This SuperSeries is composed of the following subset Series: GSE36458: Affymetrix SNP 6.0 array data for colon, gastric and esophageal adenocarcinoma cancer types GSE36459: Affymetrix 250K StyI SNP array data for gastric and esophageal adenocarcinoma cancer types Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-08-31 | E-GEOD-36460 | biostudies-arrayexpress
TranscriptomicsPatterns of gene expression and copy-number alterations in VHL disease-associated and sporadic ccRCC
Recent insights into the role of the VHL tumor suppressor gene in hereditary and sporadic clear cell carcinoma of the kidney (ccRCC) have led to new treatments for patients with metastatic ccRCC, although virtually all patients eventually succumb to the disease. We performed an integrated, genome-wi...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-14994 | biostudies-arrayexpress
UnknownGene expression profiling of 151 pediatric low-grade gliomas
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-60898 | biostudies-other
TranscriptomicsIntegrated genomic profiling of endometrial carcinoma
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation Although 75% of endometrial cancers are treated at an early stage, 15% to 20% of these recur. We performed an integrated analysis of genome-wide expression and copy-number dat...
ORGANISM(S): Homo sapiens 
2009-03-23 | E-GEOD-14860 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of MYC-amplified medulloblastoma cell lines treated by JQ1, a BET bromodomain inhibitor
MYC-amplified medulloblastomas are highly lethal tumors. BET bromodomain inhibition was recently described to downregulate MYC-associated transcriptional activity in various cancer subtypes. To investigate whether JQ1, a BET bromodomain inhibitor is downregulation MYC and MYC-associated transcriptio...
ORGANISM(S): Homo sapiens 
2013-12-02 | E-GEOD-51020 | biostudies-arrayexpress
UnknownCloneSifter: enrichment of rare clones from heterogeneous cell populations.
Not available
S-EPMC7687773 | biostudies-literature
TranscriptomicsGene expression profiling of 151 pediatric low-grade gliomas
We performed gene expression profiling on 151 paraffin-embedded PLGGs from different locations, ages, histological subtypes as well as BRAF genetic status We also compared molecular differences to normal pediatric brain expression profiles to observe whether those patterns were mirrored in normal br...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-60898 | biostudies-arrayexpress
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