Bestatin - OmicsDI

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CHEBI ID

CHEBI:3070 (7)
CHEBI:7916 (6)
CHEBI:17368 (6)
CHEBI:17895 (5)
CHEBI:17884 (5)
CHEBI:24813 (5)
CHEBI:16349 (5)
CHEBI:16424 (5)
CHEBI:29016 (5)
CHEBI:34230 (5)
CHEBI:17033 (5)
CHEBI:17311 (5)
CHEBI:17509 (5)
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CHEBI:78759 (4)
CHEBI:27915 (4)
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CHEBI:28579 (4)
CHEBI:28123 (4)
CHEBI:17747 (4)
CHEBI:46961 (4)
CHEBI:16015 (4)
CHEBI:116314 (4)
CHEBI:71466 (4)
CHEBI:18050 (4)

Metabolite Name

Bestatin (20)
Uracil (12)
Lumichrome (11)
Taurine (11)
Adenine (11)
Creatinine (11)
Indole (10)
Inosine (10)
Pseudouridine (10)
Glutathione (10)
Indolelactic acid (10)
Xanthosine (9)
Ricinoleic acid (9)
Allantoin (9)
Uridine (9)
Palmitic acid (9)
Maltotetraose (9)
Creatine (9)
Cytosine (9)
Cholic acid (8)
Hypoxanthine (8)
Deoxyguanosine (8)
Uric acid (8)
Thymidine (8)
Myristic acid (8)
Oleic acid (8)
Azelaic acid (8)
Linoleic acid (8)
Pantothenol (8)
Ile-Pro (8)

First Public Date

2022 (1)
2018 (1)
2013 (1)

Study type

ChIP-chip by array (5)
Other (2)
RIP-chip by array (1)
RNAi profiling by array (1)
Transcription profiling by array (1)
RNA-seq of coding RNA (1)

Release Date

2011 (5)
2010 (5)
2021 (5)
2016 (4)
2012 (4)
2025 (4)
2023 (4)
2020 (4)
2013 (3)
2024 (3)
2017 (3)
2014 (2)
2009 (2)
2008 (2)
2022 (2)
2019 (2)
2015 (2)
2006 (2)
2018 (1)
2007 (1)
2005 (1)

Lab affiliation

1Laboratory of Vector-Pathogen Biology, Proteomic Platform, Departmet of Molecular Biology, Université Libre de Bruxelles (1)
Biochemistry & Molecular Biology Department and Plant Resilience Institute, Michigan State University (1)
Cellzome - a GSK company (1)
Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Paul-Wittsack Str. 10, 68163 Mannheim, Germany (1)
Chair of Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany (1)
Chair, Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida (1)
Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA (1)
Chemistry department, Duke university (1)
Core Unit Mass Spectrometry and Proteomics Medical faculty Ulm University Germany (1)
Dapartment of Biochemistry, Molecular and Structural Biology Jozef Stefen Institute Ljubljana, Slovenia (1)
Department of Biochemistry & Molecular Biology Michigan State University (1)
Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg im Breisgau, Germany (1)
Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, CIBBS and BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg im Breisgau, Germany (1)
Department of Biochemistry and Molecular Biology and Agricultural Chemistry and Soil science University of Alicante SPAIN (1)
Department of Chemical & Systems Biology, Stanford University (1)
Department of Chemistry, Johns Hopkins University (1)
Department of Chemistry, T.C. Jenkins Department of Biophysics, Department of Biology, Johns Hopkins University (1)
Department of Obstetrics, Gynecology, and Reproductive Sciences, Center for Reproductive Sciences, University of California, San Francisco, CA 94143, USA Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA Department of Anatomy, University of California, San Francisco, CA 94143, USA (1)
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University (1)
Department of Plant Pathology, University of California, Davis (1)
Duke University (1)
EDyP (1)
Eppley Institute University of Nebraska Medical Center (1)
Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Straße 3, 06120, Halle/Saale, Germany Institute of Chemical Biology, National Hellenic Research Foundation, Athens, 11635, Greece (1)
Memorial Sloan Kettering Cancer Center (1)
Professor, Chemistry, Duke University (1)
School of Biosciences The University of Sheffield Western Bank Sheffield S10 2TN (1)
School of Integrative Plant Science Plant Biology Section, Cornell University (1)
Ulm University, Department of Molecular Genetics and Cell Biology, Ulm, Germany (1)
University of Auckland (1)

Tags

xref:PubMed:36649711 (1)

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Target identification of methyl bestatin

Target identification of methyl bestatin (MeBs) using the photoreactive diazirine-alkyne probe, CQ83.

ORGANISM(S): Homo sapiens (Human)

2022-11-22 | PXD038233 | Pride

RNA-seq of MV4 11 cells treated with Methyl Bestatin or Brefeldin A

PRJNA824531 | ENA

RNA-seq of MV4;11 cells treated with Methyl Bestatin or Brefeldin A

We report the application of RNA-seq for profiling gene transcription upon treatment of methyl bestatin (MeBs, aminopeptidase inhibitor) or brefeldin A (BFA, ER-to-Golgi transport inhibitor), compared to DMSO control. We found MeBs and BFA similarly upregulated genes pertinent to proteotoxic stress.

ORGANISM(S): Homo sapiens

2022-11-15 | GSE200454 | GEO

Inhibition of LTA4H by bestatin in human and mouse colorectal cancer.

Not available

S-EPMC6604047 | biostudies-literature

Bestatin, A Pluripotent Immunomodulatory Small Molecule, Drives Robust and Long-Lasting Immune Responses as an Adjuvant in Viral Vaccines.

Not available

S-EPMC10675184 | biostudies-literature

Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase.

Not available

S-EPMC3516848 | biostudies-literature

Antiplasmodial Activity Evaluation of a Bestatin-Related Aminopeptidase Inhibitor, Phebestin.