Sort   by:  
 Page size 
TranscriptomicsGene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses
Domoic acid (DA) is a neuroexcitatory amino acid that is naturally produced by some marine diatom species of the genus Pseudo-nitzschia. Ingestion of DA-contaminated seafood by humans results in a severe neurotoxic disease known as amnesic shellfish poisoning (ASP). Clinical signs of ASP include s...
ORGANISM(S): Danio rerio 
2009-07-06 | E-GEOD-12140 | biostudies-arrayexpress
TranscriptomicsTbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex
Areas and layers of the cerebral cortex are specified by genetic programs that are initiated in progenitor cells and then, implemented in postmitotic neurons. Here, we report that Tbr1, a transcription factor expressed in postmitotic projection neurons, exerts positive and negative control over both...
ORGANISM(S): Mus musculus 
2010-07-27 | E-GEOD-22371 | biostudies-arrayexpress
TranscriptomicsFOXP3-mediated inhibition of the global gene regulator SATB1 is required for maintaining regulatory T cell commitment
Regulatory T (Treg) cells are involved in self tolerance, immune homeostasis, prevention of autoimmunity, and suppression of immunity to pathogens or tumours. The forkhead transcription factor FOXP3 is essential for Treg cell development and function as mutations in FOXP3 cause severe autoimmunity i...
ORGANISM(S): Homo sapiens 
2011-08-13 | E-GEOD-15390 | biostudies-arrayexpress
TranscriptomicsmiR-155-5p regulates immune cell recruitment to the fetal lung after choriodecidual Group B Streptococcal infection
Mechanisms underlying in utero fetal lung injury remain poorly defined, and a greater understanding of pathways regulating these processes may lead to novel therapies that prevent lung injury before birth. MicroRNAs (miRNAs) are small non-coding, endogenous RNAs that regulate gene expression and hav...
ORGANISM(S): Macaca nemestrina 
2015-08-05 | E-GEOD-60628 | biostudies-arrayexpress
UnknownCohort Profile: The LIFE-Adult-Study.
Not available
S-EPMC9908058 | biostudies-literature
Sort   by:  
 Page size