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Streptococcus pneumoniae BHN418 isolate:BHN418_ucl Genome sequencing
Streptococcus pneumoniae BHN418 Genome sequencing and assembly
Here, we examined how pneumococci adapt to the upper respiratory tract conditions, and how this affects interactions with the host. We established the intranasal microenvironment including metal ion and monosaccharide concentrations to create in vivo-mimicking medium to study pneumococcal adaptation...
ORGANISM(S): Streptococcus pneumoniae 
2026-08-14 | PXD072730 | Pride
RNA-seq was performed in this study in order to identify whether the introduction of a gene mutation in S. pneumoniae, has any effect increase or decrease expression of any S. pneumoniae genes in the mutant strains that previous publications suggest might affect the safe use of these strains in huma...
ORGANISM(S): Streptococcus pneumoniae 
Rapid adaptation to grow within the physiological conditions found in the host environment is an essential but poorly understood virulence requirement for systemic pathogens such as Streptococcus pneumoniae. We have now demonstrated an essential role for the one-carbon metabolism pathway and a condi...
ORGANISM(S): Streptococcus pneumoniae 
Inflammation of the Nasal Mucosa is Associated with Susceptibility to Experimental Pneumococcal Challenge in Older Adults
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