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Global CO2 level presently recorded at 400 ppm is expected to reach 550 ppm in 2050, an increment likely to impact plant growth and productivity. Using targeted LC-MS and GC-MS platforms we quantified 229 and 29 metabolites, respectively in a time-course study to reveal short-term responses to diffe...
2017-04-25 | MTBLS311 | MetaboLights
Anthropogenic CO2 presently at 400 ppm is expected to reach 550 ppm in 2050, an increment expected to affect plant growth and productivity. Paired stomatal guard cells (GCs) are the gate-way for water, CO2, and pathogen, while mesophyll cells (MCs) represent the bulk cell-type of green leaves mainly...
2017-03-31 | MTBLS309 | MetaboLights
In an effort to begin to delineate the bicarbonate regulon, we used microarray analysis with cells grown to late exponential growth phase (3 hr) and then submitted to a 15 min exposure with 0.1 M NaHCO3. Our goal was to define the first set of genes affected by the presence of bicarbonate.
ORGANISM(S): Enterococcus faecalis 
A mathematical model of the pancreatic duct cell generating high bicarbonate concentrations in pancreatic juice David C Whitcomb, G Bard Ermentrout, Pancreas 2004 29:e30-40; PubMedID:15257112 Abstract: OBJECTIVE: To develop a simple, physiologically based mathema...
2024-09-02 | BIOMD0000000327 | BioModels
Analysis of gene expression in Pseudonocardia dioxanivorans strain CB1190 during growth with H2/bicarbonate or pyruvate Two treatments, based on carbon/energy source used for growth: pyruvate and H2/bicarbonate. Triplicate microarrays (biological replicates) were prepared for each treatment. Pyruvat...
ORGANISM(S): Pseudonocardia dioxanivorans CB1190 
Climate change as a consequence of increasing atmospheric CO2 affects plant growth and productivity. CO2 is not only a carbon donor for photosynthesis but also an environmental signal that can perturb cellular redox homeostasis and lead to modifications of redox-sensitive proteins. Although redox re...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2017-02-14 | PXD004963 | Pride
Growth of 3 related Bacillus strains in a semi-defined medium in two different atmospheres (14% CO2 and high aeration)
ORGANISM(S): Bacillus cereus 
Identification of the targets of RegA with and without bicarbonate stimulation by comparing RegA knockout to multicopy RegA transgenics. RegA is an AraC like transcription factor identified in a mutational screen for virulence genes in Citrobacter rodentium, an attaching and effacing pathogen that ...
ORGANISM(S): Citrobacter rodentium 
Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer
Oxidation of thiol proteins and redox signaling occur in cells exposed to H2O2 but mechanisms are unclear. We used redox proteomics to seek evidence of oxidation of specific proteins either by a mechanism involving reaction of H2O2 with CO2/bicarbonate to give the more reactive peroxymonocarbonate...
ORGANISM(S): Homo Sapiens 
2024-07-08 | PXD053738 |
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