Sort   by:  
 Page size 
ProteomicsAortic Aneurysm iTRAQ HiRIEF proteomics
Conducted proteomics on samples from patients with aortic aneurysm and from non-dilated controls. Furthermore, we investigated both patients with bicuspid aortic valves (BAV) and also the more normal tricuspid aortic valves (TAV). The aim was to elucidate the molecular mechanisms behind the higher p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080837 | MassIVE
TranscriptomicsTranscription profiling of human patients with aortic aneurysms associated with tricuspid and bicuspid valves
Patients with bicuspid aortic valve (BAV) have increased risk of thoracic ascending aortic aneurysm (AscAA) and dissection compared to those with a normal tricuspid aortic valve (TAV). The present study was undertaken to evaluate whether differences in gene expression exist in aortas from BAV and TA...
ORGANISM(S): Homo sapiens 
2009-02-07 | E-GEOD-5180 | biostudies-arrayexpress
ProteomicsAortic smooth muscle cells in bicuspid valve patients
and with higher incidence if associated to bicuspid aortic valve (BAV) for unknown reasons. TAA is usually diagnosed fortuitously and the lack of effective drug therapy to delay progression and avoid dissection lies in the limited knowledge of pathophysiology. Objectives. We aimed to identify the mo...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD043062 | Pride
Aortic aneurysm  bicuspid aortic valve  cardiovascular disease  vascular smooth muscle cells  proteomics 
TranscriptomicsMiRNA microarray analysis of human bicuspid and tricuspid aortic valve leaflet tissues
Bicuspid aortic valve (BAV) is a common congenital cardiac anomaly, with an estimated incidence of 1-2%. It is responsible for the greatest burden of aortic valve disease in patients younger than 70 years in North America. We performed microRNA profiling in end-stage valve leaflets with BAV and TA...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-30197 | biostudies-arrayexpress
ProteomicsAorta-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease
Bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease in general population and is frequently associated with the development of thoracic aortic aneurysm (TAA). There is no effective strategy to intervene with TAA progression due to an incomplete understanding of the patho...
ORGANISM(S): Homo sapiens (Human) 
2021-09-11 | PXD026303 | Pride
Mitochondrial dynamics Human aortic smooth muscle cells Organ-on-a-chip Thoracic aortic aneurysm Bicuspid aortic valve 
Genomics
Sequencing study of bicuspid aortic valve
PRJNA724868 | ENA
Methylation profilingEpigenome analysis of ascending aorta from normal, aortic dissection and bicuspid aortic valve patients
Genome wide DNA methylation profiling of ascending aorta tissue samples from normal, aortic dissection and bicuspid aortic valve patients with aortic dilation. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across more than 450,000 CpGs in ascen...
ORGANISM(S): Homo sapiens 
2019-07-11 | GSE84274 | GEO
GenomicsGenetic Variation Associated with Bicuspid Aortic Valve in Turner Syndrome
Genetic Variation Associated with Bicuspid Aortic Valve in Turner Syndrome
PRJNA432472 | ENA
GenomicsGenetic Variation Associated with Bicuspid Aortic Valve in Turner Syndrome
Genetic Variation Associated with Bicuspid Aortic Valve in Turner Syndrome
PRJNA432473 | ENA
UnknownClinical implications of the biomechanics of bicuspid aortic valve and bicuspid aortopathy.
Not available
S-EPMC9411999 | biostudies-literature
Sort   by:  
 Page size