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MetabolomicsFrom Microbiota to Metabolomics: How Bifidobacterium infantis YLGB-1496 Shields Neonates from Necrotizing enterocolitis

Bifidobacterium species are recognized as essential primary colonizers of the infant gastrointestinal tract and constitute a critical component of infant formula. Nevertheless, the precise mechanisms by which Bifidobacterium confers its protective effects against gut inflammation remain insuffici...

2025-10-20 | MTBLS13018 | MetaboLights
MetabolomicsLacto-N-tetraose mediates indole-3-lactic acid production by Bifidobacterium longum subsp. infantis to alleviate enterotoxigenic Escherichia coli-induced diarrhea in infants

Enterotoxigenic Escherichia coli (ETEC) is a leading cause of infectious diarrhea and poses a threat to infant health. Current treatments for ETEC infection primarily rely on antibiotics，which face limitations due to resistance and side effect. In this cross-sectional study, we analyzed fecal met...

2025-08-24 | MTBLS12886 | MetaboLights
ProteomicsBifidobacterium longum subsp. infantis utilizes urea as a nitrogen source
Bifidobacterium longum subsp. infantis is a bacterial commensal that colonizes the breast-fed infant gut where it utilizes indigestible components delivered in human milk. Accordingly, human milk contains several non-protein nitrogenous molecules, including urea at high abundance. This project inves...
ORGANISM(S): Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) 
2023-03-22 | PXD019401 | Pride
Bifidobacteria  microbiota  human milk  microbiome  urea 
TranscriptomicsRNA sequencing of Bifidobacterium longum subsp. infantis in response to various substrates
The purpose of this project was to determine the whole transcriptome response of Bifidobacterium longum subsp. Infantis to pooled and individual human milk oligosaccharides (HMO) relative to lactose Bacterial isolates grown on lactose, pooled human milk oligosaccharides (HMO), lacto-N-tetraose (LNT)...
ORGANISM(S): Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 
2015-10-28 | E-GEOD-58773 | biostudies-arrayexpress
GenomicsBifidobacterium longum subsp. infantis
Bifidobacterium longum subsp. infantis Y46 genome sequencing
PRJNA909931 | ENA
ProteomicsSuccession of Bifidobacterium longum strains in response to a changing early life nutritional environment reveals dietary substrate adaptations
Diet-microbe interactions play a crucial role in infant development and modulation of the early-life microbiota. The genus Bifidobacterium dominates the breast-fed infant gut, with strains of B. longum subsp. longum (B. longum) and B. longum subsp. infantis (B. infantis) particularly prevalent withi...
ORGANISM(S): Bifidobacterium longum subsp. longum 
2020-07-15 | PXD017277 | Pride
Cellobiose Bifidobacterium 2'fucosyllactose Lactoneotetraose 
GenomicsBifidobacterium longum subsp. infantis
Genome sequencing of Bifidobacterium longum subsp. infantis
PRJNA882778 | ENA
GenomicsBifidobacterium longum subsp. infantis
Bifidobacterium longum subsp. infantis Genome sequencing and assembly
PRJNA661151 | ENA
TranscriptomicsBifidobacterium longum subsp. infantis transcriptomes in response to various nitrogen sources
The purpose of this project was to determine the whole transcriptome response of Bifidobacterium longum subsp. infantis to human milk urea compared to complex nitrogen and L-cysteine.
ORGANISM(S): Bifidobacterium longum subsp. infantis 
2022-09-30 | GSE155078 | GEO
GenomicsBifidobacterium longum subsp. infantis strain:BT1
Bifidobacterium longum subsp. infantis strain:BT1 Genome sequencing
PRJNA270905 | ENA
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