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TranscriptomicsTranscription profiling by array of Huh7.5 cells infected with Hepatitis C Virus Jc1
Huh7/5-2 cells (Binder et al., Hepatology 2007) were mock infected (DMEM) (time points 4 and 48 h) or infected with the chimeric HCV virus Jc1 (Pietschmann et al., PNAS 2006) (all time points). Multiplicity of infection was 15 (TCID50). Cells were lysed after 4, 12, 24, 48 and 72 hours post infecti...
ORGANISM(S): Homo sapiens 
2012-06-30 | E-MTAB-1148 | biostudies-arrayexpress
ProteomicsDCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
Targeted protein degradation (TPD) mediates protein level through small molecule induced redirection of E3 ligases to ubiquitinate neo-substrates and mark them for proteasomal degradation. TPD has recently emerged as a key modality in drug discovery. So far only a few ligases have been utilized for ...
ORGANISM(S): Homo sapiens (Human) 
2023-12-18 | PXD046286 | Pride
Tmt Dcaf1 Tpd Protac 
ProteomicsRapid detection and capture of clinical Escherichia coli strains mediated by OmpA-targeting nanobodies
Escherichia coli is a major cause of blood stream and urinary tract infections. Owing to the spread of antimicrobial resistance, it is often treated with an inadequate antibiotic. With the aim to accelerate the diagnostics of this key pathogen, we used the flycode technology to generate nanobodies a...
ORGANISM(S): Escherichia coli 
2025-06-11 | PXD054264 | Pride
Lc-ms/ms Nestlink E. coli 
UnknownConventional versus rapid-deployment aortic valve replacement: a single-centre comparison between the Edwards Magna valve and its rapid-deployment successor.
Not available
S-EPMC4986793 | biostudies-literature
UnknownIntermediate-term outcome of 500 consecutive rapid-deployment surgical aortic valve procedures†.
Not available
S-EPMC6381385 | biostudies-literature
MetabolomicsToxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts
Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to enhance the number of relevant findings. The presen...
2023-10-10 | MTBLS1481 | MetaboLights
ProteomicsTotal proteome analysis of A549 IFNR knockout and HepG2 cells
Total proteome analysis of A549 IFNR knockout and HepG2 cells
ORGANISM(S): Homo sapiens (Human) 
2023-08-08 | PXD031406 | Pride
Lc-ms/ms 
ProteomicsNUDT2 Knockout full proteome mouse
Proteome comparison between bone-marrow cells isolated from wildtype and NUDT2 knockout mice.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD023219 | Pride
Mouse Full proteome Lc-ms Nudix hydolases Bone-marrow 
TranscriptomicsExpression data from primary Glioblastoma in adults
Gene expression profiling revealed over-representation of a distinct (proneural-like) expression signature in long-term survivors that was linked to IDH1/2 mutation. However, among the IDH1/2-wildtype patients, tumors from long-term survivors did not show distinct gene expression profiles and includ...
ORGANISM(S): Homo sapiens 
2014-03-27 | E-GEOD-53733 | biostudies-arrayexpress
UnknownK27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation
Not available
S-SCDT-10_15252-EMBJ_2021110145 | biostudies-other
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