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MetabolomicsFlow cytometry has a significant impact on the cellular metabolome (CE-MS assay)
The characterization of specialized cell subpopulations in a heterogeneous tissue is essential for understanding organ function in health and disease. A popular method of cell isolation is fluorescence-activated cell sorting (FACS) based on probes that bind surface or intracellular markers. In this ...
2018-11-06 | MTBLS633 | MetaboLights
MetabolomicsFlow cytometry has a significant impact on the cellular metabolome (GC-MS assay)
The characterization of specialized cell subpopulations in a heterogeneous tissue is essential for understanding organ function in health and disease. A popular method of cell isolation is fluorescence-activated cell sorting (FACS) based on probes that bind surface or intracellular markers. In this ...
2018-11-06 | MTBLS634 | MetaboLights
MetabolomicsFlow cytometry has a significant impact on the cellular metabolome (General LC-MS assay)
The characterization of specialized cell subpopulations in a heterogeneous tissue is essential for understanding organ function in health and disease. A popular method of cell isolation is fluorescence-activated cell sorting (FACS) based on probes that bind surface or intracellular markers. In this ...
2018-11-06 | MTBLS629 | MetaboLights
MetabolomicsFlow cytometry has a significant impact on the cellular metabolome (Lipidomic LC-MS assay)
The characterization of specialized cell subpopulations in a heterogeneous tissue is essential for understanding organ function in health and disease. A popular method of cell isolation is fluorescence-activated cell sorting (FACS) based on probes that bind surface or intracellular markers. In this ...
2018-11-06 | MTBLS631 | MetaboLights
ProteomicsMultisystem inflammatory syndrome in children (MIS-C) serum proteomics
While fewer cases of severe Coronavirus Disease 2019 (COVID-19) are reported globally in children, a small proportion of SARS-CoV-2 infected children develop a novel pediatric febrile entity called multisystem inflammatory syndrome in children (MIS-C) that develops 2 to 5 weeks after initial SARS-Co...
ORGANISM(S): Homo sapiens (Human) 
2021-09-29 | PXD025462 | Pride
Mis-c Proteomics Dia Serum Lc-ms 
ProteomicsHuman HFpEF Myocardial Proteomics
Background: Heart failure with preserved ejection fraction (HFpEF) constitutes more than half of all heart failure but has few effective therapies. Recent human myocardial transcriptomics and metabolomics have revealed major differences between HFpEF, HF with reduced EF (HFrEF), and controls. How th...
ORGANISM(S): Homo sapiens (Human) 
2024-03-05 | PXD045677 | Pride
Proteomics Myocardium Obesity Molecular medicine Heart disease Human 
ProteomicsMyocardial Proteome in Human Heart Failure with Preserved Ejection Fraction
Background: Heart failure with preserved ejection fraction (HFpEF) constitutes more than half of all heart failure but has few effective therapies. Recent human myocardial transcriptomics and metabolomics have revealed major differences between HFpEF, HF with reduced EF (HFrEF), and controls. How th...
ORGANISM(S): Homo sapiens (Human) 
2025-04-11 | PXD060431 | Pride
Oxidative phosphorylation Metabolism Fatty acids Proteomics Obesity Myocardium Molecular medicine : heart failure 
ProteomicsQCeltis Case Study 1: Depleted Plasma QC Dataset
A dataset containing depleted plasma samples used as quality control technical replicates (TR) and digestion replicates (DR). Plasma aliquot was shunted to Top14 Abundant Protein Depletion Resin (A36372) based depletion. Depleted plasma samples were processed on a i7 automated liquid handling system...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000095742 | MassIVE
ProteomicsDepletion of Mitochondrial Methionine Adenosyltransferase α1 Triggers Mitochondrial Dysfunction in Alcohol-Associated Liver Disease
Mitochondrial MATα1 is selectively depleted in alcohol-associated liver disease through a mechanism that involves the isomerase PIN1 and the kinase CK2. Alcohol activates CK2, which phosphorylates MATα1 at Ser114 facilitating interaction with PIN1, thereby inhibiting its mitochondrial localization. ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-02-17 | PXD030383 | Pride
Liver Matα1 Mitochondria Alcohol 
ProteomicsStandardized workflow for precise mid- and high-throughput proteomics of blood biofluids
Background: Accurate discovery assay workflows are critical for identifying authentic circulating protein biomarkers in diverse blood matrices. Maximizing the commonalities in the proteomic workflows between different biofluids simplifies the approach and increases the likelihood for reproducibility...
ORGANISM(S): Homo Sapiens 
2022-05-11 | PXD024884 | panorama
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