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ProteomicsCRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neurodegeneration
Accumulation of aggregated and misfolded proteins, leading to endoplasmic reticulum stress and activation of the unfolded protein response, is a hallmark of several neurodegenerative disorders, including Alzheimer’s and Parkinson’s disease. Genetic screens are powerful tools that are proving invalua...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD038395 | Pride
Cortical neurons Kat2b L-moses Endoplasmic reticulum (er) stress Acetylome 
UnknownHIV prevalence, testing and treatment among men who have sex with men through engagement in virtual sexual networks in Kenya: a cross-sectional bio-behavioural study.
Not available
S-EPMC7319161 | biostudies-literature
UnknownReal-World Dose Escalation and Associated Direct Costs of Biologics in Management of Ulcerative Colitis: A Retrospective Database Study.
Not available
S-EPMC12503804 | biostudies-literature
UnknownConstipation-Predominant Irritable Bowel Syndrome Females Have Normal Colonic Barrier and Secretory Function.
Not available
S-EPMC5502210 | biostudies-literature
UnknownStudy protocol of a randomised controlled trial of prostate radiotherapy in high-risk and node-positive disease comparing moderate and extreme hypofractionation (PRIME TRIAL).
Not available
S-EPMC7050316 | biostudies-literature
UnknownGLORIA - A globally representative hyperspectral in situ dataset for optical sensing of water quality.
Not available
S-EPMC9935528 | biostudies-literature
UnknownA map of African humid tropical forest aboveground biomass derived from management inventories.
Not available
S-EPMC7343822 | biostudies-literature
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