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MetabolomicsDiagnostic utility of clinicodemographic, biochemical and metabolite variables to identify viable pregnancies in a symptomatic cohort during early gestation.

Study question: Can a novel machine learning pipeline create predictive models that identify a composite biomarker to differentiate live normally sited pregnancies (LNSP) from non-viable pregnancies in women presenting with pain and/or bleeding in early gestation?

Summary answer: Serum met...

2025-08-14 | MTBLS6219 | MetaboLights
UnknownBiochemical reconstitution of topological DNA binding by the cohesin ring.
Not available
S-EPMC3907785 | biostudies-literature
UnknownDurable vesicles for reconstitution of membrane proteins in biotechnology.
Not available
S-EPMC5310719 | biostudies-literature
UnknownReconstitution and biochemical characterization of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems.
Not available
S-EPMC6607021 | biostudies-literature
UnknownBiochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Not available
S-EPMC4778062 | biostudies-literature
MetabolomicsBiosynthesis of Isonitrile Lipopeptides by Conserved Non-ribosomal Peptide Synthetase Gene Clusters in Actinobacteria
A putative lipopeptide biosynthetic gene cluster is conserved in many species of Actinobacteria, including Mycobacterium tuberculosis and Mycobacterium marinum, but the specific function of the encoding proteins has been elusive. Using both in vivo heterologous reconstitution and in vitro biochemica...
2017-07-18 | MTBLS454 | MetaboLights
UnknownBiochemical reconstitution of temozolomide-induced mutational processes.
Not available
S-EPMC12556801 | biostudies-literature
UnknownGenetic and Biochemical Reconstitution of Bromoform Biosynthesis in Asparagopsis Lends Insights into Seaweed Reactive Oxygen Species Enzymology.
Not available
S-EPMC7306000 | biostudies-literature
ProteomicsFAF2 enhances unfoldase activity of mammalian p97-UFD1-NPL4 complex enabling rational design of p97
To address how adaptor proteins impact human p97 activity, we here employ in vitro reconstitution and a focused biochemical screen to identify adaptors that enhance unfoldase activity of human p97 in the presence of UFD1-NPL4. Of the adaptors tested, Fas-associated factor 2 (FAF2/UBXD8), a UBX domai...
ORGANISM(S): Homo sapiens (Human) 
2026-07-28 | PXD073479 | Pride
Faf2 Hdx-ms P97 
UnknownBiochemical reconstitution of UV-induced mutational processes.
Not available
S-EPMC6648339 | biostudies-literature
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