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MetabolomicsSynergistic metabolism of salivary MUC5B in oral commensal bacteria during early biofilm formation

Bacterial metabolism in oral biofilms is comprised of complex networks of nutritional chains and biochemical regulations. These processes involve both intraspecies and interspecies networks as well as interactions with components from host saliva, gingival crevicular fluid, and dietary intake. In...

2023-10-30 | MTBLS8370 | MetaboLights
MetabolomicsModerate salinity restricts the transformation depth of norfloxacin by halotolerant Chlorella sp. AMC-2: Physiological adaptation and metabolic reprogramming
Despite increasing application of microalgae for antibiotic-contaminated aquaculture wastewater treatment, how salinity regulates antibiotic transformation depth and cellular adaptation remains unclear. This study combined salinity-gradient cultivation, process partitioning, transformation-product p...
2026-10-01 | MTBLS15888 | MetaboLights
ProteomicsBiofilm-driven LPS remodeling and colanic acid overproduction mediate Triamine adaptation and antibiotic cross-resistance in E. coli
The identification of the determinants driving antimicrobial resistance is a prerequisite for improving the control of resistance emergence and dissemination. Disinfectant biocides, daily used in food-processing industries, have already been associated with the cross-selection of antibiotic-resistan...
ORGANISM(S): Escherichia coli Bacteria 
2026-07-02 | PXD071663 | Pride
Colanic acid Biofilm adaptation Biocides Lipopolysaccharide Cross-resistance Antimicrobial resistance 
TranscriptomicsPseudomonas aeruginosa biofilm cells contain ribosome hibernation factors in the dormant antibiotic-tolerant subpopulation
Bacteria growing in biofilms are physiologically heterogeneous, due in part to their adaptation to local environmental conditions. Here, we characterized the local transcriptional responses of Pseudomonas aeruginosa growing in biofilms by using microarray analysis of isolated biofilm subpopulations....
ORGANISM(S): Pseudomonas aeruginosa 
2012-05-02 | E-GEOD-34762 | biostudies-arrayexpress
ProteomicsMetabolic changes in adaptation to biofilm growth by streptococcus pneumoniae
Comparative analyses of protein expression between log-phase planktonic and 1-day and 7-day biofilm cultures from Streptococcus pneumoniae representing nascent and late phase biofilm growth were performed using the proteomic approach iTRAQ
ORGANISM(S): Streptococcus pneumoniae SP14-BS69 
2014-09-10 | PXD001182 | Pride
Biofilm Streptococcus pneumoniae 
UnknownCo-culture biofilm patterns among different Pseudomonas aeruginosa clones from cystic fibrosis patients.
Not available
S-EPMC11834076 | biostudies-literature
GenomicsCharacterization of the cellular adaptation during biofilm formation in Gram positive bacteria
Characterization of the cellular adaptation during biofilm formation in Gram positive bacteria
PRJNA682641 | ENA
TranscriptomicsCharacterization of the cellular adaptation during biofilm formation in Gram positive bacteria
Cellular adaptation during biofilm formation in Gram positive bacteria
ORGANISM(S): Staphylococcus aureus Enterococcus faecalis 
2020-12-05 | GSE162709 | GEO
TranscriptomicsCharacterizing the transcriptional adaptation of Staphylococcus aureus to stationary phase growth
Staphylococcus aureus is an important human pathogen that causes life-threatening infections, and is resistant to the majority of our antibiotic arsenal. This resistance is complicated by the observation that most antibacterial agents target actively growing cells, thus, proving ineffective against ...
ORGANISM(S): Staphylococcus aureus 
2016-05-18 | E-GEOD-77242 | biostudies-arrayexpress
TranscriptomicsAcid-inducible genes in Streptococcus mutans: multiple two-component systems involved in acid adaptation
Global transcriptional analysis of acid-inducible genes in Streptococcus mutans: multiple two-component systems involved in acid adaptation pH is a major environmental factor that regulates gene expression in many bacteria. Streptococcus mutans in dental biofilms is regularly exposed to cycles of a...
ORGANISM(S): Streptococcus mutans 
2010-05-22 | E-GEOD-15125 | biostudies-arrayexpress
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